The inhibitory effect of nebulized albuterol on the early and late asthmatic reactions and increase in airway responsiveness provoked by inhaled allergen in asthma.

Author: FinnertyJ P, HolgateS T, TwentymanO P

Paper Details 
Original Abstract of the Article :
It is widely held that inhaled beta 2-adrenoceptor agonists inhibit the early asthmatic response (EAR) but not the late response (LAR) or attendant increase in bronchial responsiveness. In this study of 10 atopic asthmatic subjects, we have investigated the effects of a high dose of nebulized albute...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1164/ajrccm/144.4.782

データ提供:米国国立医学図書館(NLM)

The Inhibitory Effect of Nebulized Albuterol on the Early and Late Asthmatic Reactions and Increase in Airway Responsiveness Provoked by Inhaled Allergen in Asthma

This research dives into the complex world of asthma, exploring the effects of albuterol, a common bronchodilator, on various stages of asthmatic reactions. The study is like a scientific expedition through the vast desert of asthma research, seeking to understand how albuterol interacts with the different phases of an asthmatic response. Researchers meticulously studied 10 atopic asthmatic subjects, carefully monitoring their reactions to inhaled allergens both with and without albuterol treatment. Their findings, like a precious oasis in the harsh desert environment, offer valuable insights into the effectiveness of albuterol in managing asthma symptoms.

Albuterol Effectively Inhibits Both Early and Late Asthmatic Reactions

This study reveals that albuterol, when administered before allergen exposure, effectively inhibits both the early and late asthmatic reactions, as well as the increase in airway responsiveness. It's like finding a protective shield in the desert, offering a safe haven from the harsh elements. The researchers found that albuterol significantly reduced the decline in lung function associated with both early and late asthmatic reactions, suggesting its potential for effectively controlling asthma symptoms. This finding is like discovering a hidden spring in the desert, providing a source of hope for managing asthma and improving patient quality of life.

Implications for Asthma Management

This study offers valuable insights into the effectiveness of albuterol in managing asthma symptoms. It's like learning how to navigate the desert by understanding the terrain, recognizing the different phases of an asthmatic response and utilizing the appropriate tools for managing each phase. The findings suggest that albuterol, when administered prophylactically, can significantly reduce the severity of both early and late asthmatic reactions, potentially preventing the development of more severe symptoms. This research encourages a more proactive approach to asthma management, emphasizing the importance of early intervention and the use of appropriate medications to control asthma symptoms and improve patient outcomes.

Dr.Camel's Conclusion

This research, like a journey through the desert of asthma research, reveals the effectiveness of albuterol in inhibiting both early and late asthmatic reactions. The findings encourage a more proactive approach to asthma management, emphasizing the importance of early intervention and the use of appropriate medications to control asthma symptoms and improve patient outcomes.

Date :
  1. Date Completed 1991-11-01
  2. Date Revised 2015-11-19
Further Info :

Pubmed ID

1928949

DOI: Digital Object Identifier

10.1164/ajrccm/144.4.782

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.