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The inhibitory effect of nebulized albuterol on the early and late asthmatic reactions and increase in airway responsiveness provoked by inhaled allergen in asthma.
Author: FinnertyJ P, HolgateS T, TwentymanO P
Original Abstract of the Article :
It is widely held that inhaled beta 2-adrenoceptor agonists inhibit the early asthmatic response (EAR) but not the late response (LAR) or attendant increase in bronchial responsiveness. In this study of 10 atopic asthmatic subjects, we have investigated the effects of a high dose of nebulized albute...See full text at original site
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引用元:
https://doi.org/10.1164/ajrccm/144.4.782
データ提供:米国国立医学図書館(NLM)
The Inhibitory Effect of Nebulized Albuterol on the Early and Late Asthmatic Reactions and Increase in Airway Responsiveness Provoked by Inhaled Allergen in Asthma
This research dives into the complex world of asthma, exploring the effects of albuterol, a common bronchodilator, on various stages of asthmatic reactions. The study is like a scientific expedition through the vast desert of asthma research, seeking to understand how albuterol interacts with the different phases of an asthmatic response. Researchers meticulously studied 10 atopic asthmatic subjects, carefully monitoring their reactions to inhaled allergens both with and without albuterol treatment. Their findings, like a precious oasis in the harsh desert environment, offer valuable insights into the effectiveness of albuterol in managing asthma symptoms.
Albuterol Effectively Inhibits Both Early and Late Asthmatic Reactions
This study reveals that albuterol, when administered before allergen exposure, effectively inhibits both the early and late asthmatic reactions, as well as the increase in airway responsiveness. It's like finding a protective shield in the desert, offering a safe haven from the harsh elements. The researchers found that albuterol significantly reduced the decline in lung function associated with both early and late asthmatic reactions, suggesting its potential for effectively controlling asthma symptoms. This finding is like discovering a hidden spring in the desert, providing a source of hope for managing asthma and improving patient quality of life.
Implications for Asthma Management
This study offers valuable insights into the effectiveness of albuterol in managing asthma symptoms. It's like learning how to navigate the desert by understanding the terrain, recognizing the different phases of an asthmatic response and utilizing the appropriate tools for managing each phase. The findings suggest that albuterol, when administered prophylactically, can significantly reduce the severity of both early and late asthmatic reactions, potentially preventing the development of more severe symptoms. This research encourages a more proactive approach to asthma management, emphasizing the importance of early intervention and the use of appropriate medications to control asthma symptoms and improve patient outcomes.
Dr.Camel's Conclusion
This research, like a journey through the desert of asthma research, reveals the effectiveness of albuterol in inhibiting both early and late asthmatic reactions. The findings encourage a more proactive approach to asthma management, emphasizing the importance of early intervention and the use of appropriate medications to control asthma symptoms and improve patient outcomes.
Date :
- Date Completed 1991-11-01
- Date Revised 2015-11-19
Further Info :
English
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