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Aromatase inhibitors for treatment of advanced breast cancer in postmenopausal women.

Author: BlissJudith, DawsonClaire, GibsonLorna, LawrenceDavid

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review examines the use of aromatase inhibitors (AIs) in the treatment of advanced breast cancer. While AIs have shown similar tumor-regressing effects to other endocrine treatments, the evidence regarding their response rates and side effects is still limited.
Paper Details　
Original Abstract of the Article :
Endocrine therapy removes the influence of oestrogen on breast cancer cells and so hormonal treatments such as tamoxifen, megestrol acetate and medroxyprogesterone acetate have been in use for many years for advanced breast cancer. Aromatase inhibitors (AIs) inhibit oestrogen synthesis in the periph...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7154337/

データ提供：米国国立医学図書館（NLM）

Aromatase Inhibitors for Breast Cancer

This article reviews the use of aromatase inhibitors (AIs), a class of medications that block the production of estrogen, in the treatment of advanced breast cancer in postmenopausal women. The article compares the effectiveness and side effects of different AIs, including anastrozole, exemestane, and letrozole.

Aromatase Inhibitors: A Powerful Weapon Against Breast Cancer

AIs have proven to be an effective treatment option for advanced breast cancer in postmenopausal women. The article highlights the efficacy of these drugs in inhibiting tumor growth and improving survival outcomes. However, it also emphasizes the need for careful monitoring of potential side effects, such as bone loss and hot flashes.

Navigating the Desert of Breast Cancer Treatment

Imagine advanced breast cancer as a vast and unforgiving desert, where treatment options can be limited and challenging. AIs, like a beacon in the distance, offer a potent weapon against this deadly disease. The article provides valuable insights into the use of these medications, reminding us that while powerful, they are not without potential risks. It underscores the importance of careful patient selection and personalized treatment plans to maximize benefits and minimize side effects.

Dr. Camel's Conclusion

This article sheds light on the ongoing fight against breast cancer, highlighting the importance of research and innovation in developing new and effective treatment strategies. It reminds us that while the desert of breast cancer can be daunting, we are constantly discovering new tools and treatments to combat this disease.
Date :
  1. Date Completed 2010-01-27
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

19821307

DOI: Digital Object Identifier

PMC7154337

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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