Paper Details

  1. Home
  2. Paper Details

Ribavirin monotherapy for chronic hepatitis C.

Author: BrokJesper, GluudChristian, GluudLise Lotte

ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Ribavirin monotherapy did not show any significant benefit for chronic hepatitis C patients. It did not improve sustained virological response or liver-related morbidity. However, it increased the risk of adverse reactions, including anemia.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Hepatitis C is a major cause of liver-related morbidity and mortality. A high proportion of patients never experience symptoms. Peginterferon plus ribavirin is the recommended treatment for chronic hepatitis C. However, ribavirin monotherapy may be considered for some patients. OBJECTIV...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1002/14651858.CD005527.pub2

データ提供：米国国立医学図書館（NLM）

Ribavirin: A new approach to treating chronic hepatitis C

This systematic review assesses the efficacy of ribavirin monotherapy, a single-drug treatment, for chronic hepatitis C, a viral infection that affects the liver. It's like considering a lone camel navigating a vast desert, relying solely on its own resources to reach its destination.

A complex landscape: The challenges of treating chronic hepatitis C

Chronic hepatitis C is a complex disease with a range of treatment options. This review delves into the use of ribavirin monotherapy, examining its effectiveness and comparing it to other treatment strategies. It's like exploring the different routes through a vast and challenging desert, seeking the most effective and safest path to recovery.

The limits of solitary travel: The effectiveness of ribavirin monotherapy

The review found that ribavirin monotherapy was not effective in clearing the hepatitis C virus, with no significant impact on sustained virological response. This suggests that a lone camel may not be equipped to tackle the challenges of this desert alone. The study also highlighted the potential side effects of ribavirin monotherapy, emphasizing the importance of considering the risks and benefits before embarking on this treatment path.

Dr.Camel's Conclusion

This review, like a wise camel guide, advises caution when considering ribavirin monotherapy for chronic hepatitis C. While it may offer a seemingly straightforward approach, the lack of significant effectiveness and potential side effects make it a risky venture. The journey towards treating chronic hepatitis C requires a more comprehensive and collaborative approach, like a caravan of camels working together to navigate the challenges of this desert.

Date :
  1. Date Completed 2010-01-27
  2. Date Revised 2020-05-11
Further Info :

Pubmed ID

19821346

DOI: Digital Object Identifier

10.1002/14651858.CD005527.pub2

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.