Switching from oral cholinesterase inhibitors to the rivastigmine transdermal patch.

Author: BouchardR W, GoodmanI, PerezJ A Davila, SadowskyC, TekinS

Paper Details 
Original Abstract of the Article :
Oral cholinesterase inhibitors (ChEIs) are associated with side effects such as nausea and vomiting. The use of transdermal patches for ChEI delivery may help to minimize these problems. The objective of this review was to consider available data from patients switching from oral ChEIs to transderma...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493826/

データ提供:米国国立医学図書館(NLM)

Switching Gears: From Oral Cholinesterase Inhibitors to Rivastigmine Patches

This research investigates the practicality and safety of switching patients from oral cholinesterase inhibitors (ChEIs), medications used to treat Alzheimer's disease, to the rivastigmine transdermal patch. The authors recognize that oral ChEIs often cause unpleasant side effects like nausea and vomiting. They reviewed clinical trial data and observational studies to assess the feasibility and safety of switching patients to the rivastigmine patch. Their findings suggest that this switch can be well-tolerated, with low rates of nausea and vomiting reported in patients switching from various oral ChEI medications. They also provide specific recommendations for switching regimens based on patients' previous oral ChEI dosage.

Improving Patient Comfort and Adherence

The research suggests that switching patients from oral ChEIs to the rivastigmine patch could significantly improve their quality of life by reducing bothersome side effects. It also highlights the importance of individualized treatment approaches, tailoring the switch based on a patient's specific needs and medication history. The insights gleaned from this research could help patients with Alzheimer's disease better manage their condition and potentially improve their overall well-being.

Practical Implications for Patients

For patients with Alzheimer's disease who are currently taking oral ChEIs and experiencing side effects, this study provides hope for a more comfortable and effective treatment option. It's important to discuss the potential benefits and risks of switching to the rivastigmine patch with a healthcare professional. This research also underscores the importance of patient education, empowering individuals with Alzheimer's disease to actively participate in their treatment decisions.

Dr. Camel's Conclusion

Think of switching from oral ChEIs to the rivastigmine patch as a camel caravan transitioning from a bumpy desert path to a smoother, more comfortable route. This study helps us navigate the complex world of medication management, finding ways to improve patient comfort and make the journey smoother for those battling Alzheimer's disease.

Date :
  1. Date Completed 2010-03-23
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20070789

DOI: Digital Object Identifier

PMC6493826

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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