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Triptan exposure during pregnancy and the risk of major congenital malformations and adverse pregnancy outcomes: results from the Norwegian Mother and Child Cohort Study.

Author: Nezvalová-HenriksenKaterina, NordengHedvig, SpigsetOlav

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Triptan therapy during pregnancy was not associated with an overall increased risk of congenital malformations. However, there was a slight increase in the risk of atonic uterus and hemorrhage associated with triptan use during the second and/or third trimesters.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: To evaluate the safety of triptan therapy during pregnancy. BACKGROUND: Information on the safety of triptan therapy during pregnancy is scarce and only available for sumatriptan, naratriptan, and rizatriptan. No associations with congenital malformations have been detected so far, but o...See full text at original site
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引用元：
https://doi.org/10.1111/j.1526-4610.2010.01619.x

データ提供：米国国立医学図書館（NLM）

Triptans and Pregnancy: Exploring Safety

This study investigated the safety of triptan medication during pregnancy. Imagine navigating a desert with a pregnant camel, seeking to understand the potential risks and benefits of a specific medicine. This study examined a large cohort of pregnant women in Norway, evaluating the association between triptan use and adverse pregnancy outcomes, specifically major congenital malformations. The researchers found no significant association between triptan use during the first trimester and major congenital malformations.

Triptans and Pregnancy: Potential Risks and Benefits

While triptan use during the first trimester appeared safe, the study found a slight increase in the risk of atonic uterus and hemorrhage during labor associated with triptan use during the second and third trimesters. These findings highlight the need for careful consideration of potential risks and benefits when using triptans during pregnancy.

Navigating Pregnancy with Medications

This study emphasizes the importance of careful consultation with healthcare providers regarding the use of medications during pregnancy. It's like navigating a desert with a seasoned guide, ensuring the safest route and the best possible outcome for both mother and child.

Dr. Camel's Conclusion

This study provides valuable insights into the safety of triptan use during pregnancy, emphasizing the need for careful consideration and consultation with healthcare professionals. It's like navigating a desert landscape with a map and compass, ensuring the safest route and the best possible outcome for our journey.

Date :
  1. Date Completed 2010-08-18
  2. Date Revised 2022-03-17
Further Info :

Pubmed ID

20132339

DOI: Digital Object Identifier

10.1111/j.1526-4610.2010.01619.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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