Paper Details
- Home
- Paper Details
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.
Author: AntoninoMark J, BlidenKevin P, ButlerKathleen, EikelboomJohn W, GurbelPaul A, HendersonDavid, HustedSteen, KereiakesDean J, NielsenTonny, PatelDharmendra V, RasmussenLars, Sabe-AffakiGeorges, StoreyRobert F, TantryUdaya S, TengRenli, WeiCheryl
Original Abstract of the Article :
BACKGROUND: The antiplatelet effects of the Platelet Inhibition and Patient Outcomes (PLATO) trial dose of ticagrelor in patients nonresponsive to clopidogrel and after they switch agents are unknown. METHODS AND RESULTS: Patients with stable coronary artery disease on aspirin therapy received a 30...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1161/CIRCULATIONAHA.109.919456
データ提供:米国国立医学図書館(NLM)
Ticagrelor: A Promising Alternative for Clopidogrel Nonresponders
This study explores the effectiveness of ticagrelor, a new antiplatelet medication, in patients who do not respond adequately to clopidogrel, a commonly used antiplatelet drug. The study investigates the antiplatelet effects of ticagrelor in both clopidogrel responders and nonresponders, examining the potential of switching therapies.
Overcoming Clopidogrel Nonresponsiveness with Ticagrelor
The study demonstrated that ticagrelor effectively overcomes nonresponsiveness to clopidogrel, significantly reducing platelet aggregation in patients who did not adequately respond to clopidogrel. This finding suggests that ticagrelor could be a valuable alternative for patients who are not adequately protected by clopidogrel alone.
Improved Cardiovascular Protection for High-Risk Patients
This research offers hope for individuals at high risk of cardiovascular events by providing a more effective antiplatelet treatment option for those who do not respond adequately to clopidogrel. By exploring the efficacy of ticagrelor, the study paves the way for more personalized treatment strategies tailored to individual patient needs and responses.
Dr. Camel's Conclusion
This study, like a camel caravan traversing the treacherous desert of cardiovascular disease, explores the potential of ticagrelor as a lifeline for patients who do not respond adequately to clopidogrel. The findings, like a refreshing oasis in a parched landscape, highlight the efficacy of ticagrelor in overcoming nonresponsiveness to clopidogrel, offering hope for improved cardiovascular protection for those at high risk.
Date :
- Date Completed 2010-04-07
- Date Revised 2018-12-01
Further Info :
Related Literature
English
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.