Paper Details

  1. Home
  2. Paper Details

Effects of oxcarbazepine and carbamazepine on driving ability: a double-blind, randomized crossover trial with healthy volunteers.

Author: HoffmannSonja, KaussnerYvonne, Kenntner-MabialaRamona, KlattJan, KrügerHans-Peter, TracikFerenc

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Both oxcarbazepine (OXC) and carbamazepine (CBZ) negatively affected driving performance. CBZ had a more pronounced negative effect on driving performance than OXC.
Paper Details　
Original Abstract of the Article :
RATIONALE: Carbamazepine (CBZ) is known to produce cognitive side effects being at least partly relevant for driving. In contrast to this, the cognitive effects of oxcarbazepine (OXC) are suspected to be less pronounced. OBJECTIVE: This study aimed to test 900 mg/day OXC as compared to 600 mg/day C...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1007/s00213-010-1814-y

データ提供：米国国立医学図書館（NLM）

Navigating the Impact of Antiepileptic Drugs on Driving Ability

This research dives into the fascinating, yet often overlooked, area of how antiepileptic drugs, akin to navigating a desert with shifting sands, can impact driving ability. The study, a double-blind, randomized crossover trial, compares the effects of oxcarbazepine (OXC) and carbamazepine (CBZ) on driving performance in healthy volunteers. The findings reveal that both drugs negatively impact driving performance, potentially affecting lane-keeping, increasing driving mistakes, and inducing sleepiness.

OXC – A Potential Alternative for Epileptic Drivers

The research reveals a significant finding – while both OXC and CBZ negatively affect driving performance, the negative effects of OXC tend to be less pronounced. This insight suggests that OXC may be a preferable option for epileptic patients who need to drive, offering a potential path for maintaining a degree of mobility while managing their condition.

Driving with Epilepsy – A Balancing Act

This research highlights the importance of awareness and caution for individuals with epilepsy who drive. It emphasizes the need for open communication with your doctor about any potential side effects of your medication, including those that could affect your driving ability. Remember, like navigating a desert, driving with epilepsy requires careful planning, awareness of your surroundings, and a mindful approach.

Dr.Camel's Conclusion

This study offers valuable insights into the impact of antiepileptic drugs on driving ability, highlighting the importance of careful consideration for individuals with epilepsy who drive. While both OXC and CBZ can affect driving performance, OXC may be a preferable option for maintaining a degree of mobility while managing their condition. This research serves as a guidepost, encouraging further investigation into the effects of antiepileptic drugs on driving, ultimately aiming to enhance patient safety and well-being.

Date :
  1. Date Completed 2010-12-10
  2. Date Revised 2018-12-01
Further Info :

Pubmed ID

20237772

DOI: Digital Object Identifier

10.1007/s00213-010-1814-y

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.