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Drug profile: transdermal rivastigmine patch in the treatment of Alzheimer disease.

Author: BernabeiRoberto, BlesaRafael, BullockRoger, CunhaLuis, DaniëlsHugo, DziadulewiczEdward, EmreMurat, FrölichLutz, FörstlHans, GabryelewiczTomasz, LevinOleg, LindesayJames, Martínez-LagePablo, MonschAndreas, TsolakiMagda, van LaarTeus

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study reviewed the current literature on rivastigmine patch for the treatment of Alzheimer disease. The patch provides continuous delivery of drug through the skin into the bloodstream, avoiding fluctuations in plasma concentration associated with oral administration. This pharmacokinetic profile is associated with reduced side effects, resulting in easier access to expected target doses.
Paper Details　
Original Abstract of the Article :
Cholinesterase inhibitors constitute one of the mainstays of treatment of Alzheimer disease (AD). Gastrointestinal side effects, difficulty accessing therapeutic doses and poor patient compliance have been identified as barriers to effective treatment with these substances. The rivastigmine transder...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493902/

データ提供：米国国立医学図書館（NLM）

Rivastigmine Patch: A New Oasis for Alzheimer's Disease Treatment

Alzheimer's disease (AD) is a devastating neurological condition, and finding effective treatments is a critical priority. This study explores the benefits of transdermal rivastigmine patch in managing AD. It's like discovering a new oasis in a vast desert, offering a fresh source of hope and relief. The transdermal patch provides continuous delivery of rivastigmine, a cholinesterase inhibitor, directly into the bloodstream, reducing the fluctuations in plasma concentration associated with oral administration. This leads to fewer side effects and improved patient compliance, making it a promising new option for AD treatment.

Transdermal Rivastigmine: A Smoother Journey Through the Desert of AD

The transdermal rivastigmine patch offers several advantages over oral administration, including reduced side effects and improved patient compliance. This makes it a valuable tool for managing AD, providing patients with a more comfortable and effective treatment option.

Navigating the Desert of Alzheimer's: A Patch of Hope

Think of AD as a challenging desert journey with unpredictable sandstorms. The transdermal rivastigmine patch acts like a reliable camel, providing steady and consistent support, making the journey smoother and less burdensome. This research highlights the potential of transdermal rivastigmine as a viable treatment option for AD, offering hope to patients and their families.

Dr.Camel's Conclusion

This study underscores the potential of transdermal rivastigmine patch as a promising new approach to managing Alzheimer's disease. By providing continuous drug delivery and reducing side effects, this new treatment option offers a more comfortable and effective solution for patients battling this debilitating condition. It's like discovering a new oasis in a vast desert, offering a fresh source of hope and relief.
Date :
  1. Date Completed 2010-10-21
  2. Date Revised 2021-10-20
Further Info :

Pubmed ID

20370805

DOI: Digital Object Identifier

PMC6493902

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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