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Postoperative adjuvant antiviral therapy for hepatitis B/C virus-related hepatocellular carcinoma: a meta-analysis.

Author: HuangJie-Fu, LiuChang-Ning, LuXin, MaoYi-Lei, MiaoRuo-Yu, SangXin-Ting, YangHua-Yu, ZhaoHai-Tao, ZhaoYi, ZhongShou-Xian

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This meta-analysis found that postoperative antiviral therapy, interferon in particular, may serve as a favorable alternative to reduce recurrence and mortality in patients with HBV/HCV related HCCs.
Paper Details　
Original Abstract of the Article :
AIM: To investigate the impact of postoperative antiviral treatment on tumor recurrence and survival of patients with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection-related primary hepatocellular carcinoma (HCC) after curative therapy. METHODS: We performed a meta-analysis of ...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2887591/

データ提供：米国国立医学図書館（NLM）

Fighting Hepatocellular Carcinoma: A Dual-pronged Approach

Hepatocellular carcinoma (HCC), a type of liver cancer, poses a significant health challenge. This meta-analysis investigates the impact of postoperative antiviral treatment on tumor recurrence and survival in patients with HCC associated with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection. The study seeks to understand the role of antiviral therapy in managing HCC after curative treatment.

Antiviral Therapy: A Powerful Tool in the Fight Against HCC

The meta-analysis reveals a significant benefit of postoperative antiviral therapy in reducing tumor recurrence and improving survival rates in patients with HBV/HCV-related HCC. The results suggest that antiviral therapy, particularly interferon, can be a valuable adjunct to conventional treatments, enhancing long-term outcomes for patients with this challenging disease.

HCC Management: A Multidisciplinary Approach

This meta-analysis highlights the importance of a multidisciplinary approach to managing HCC, incorporating antiviral therapy in addition to conventional treatments. It emphasizes the need for comprehensive care plans that address both the cancer and the underlying viral infection, maximizing patient chances of survival and improving long-term outcomes.

Dr.Camel's Conclusion

This meta-analysis is like a caravan of research findings, converging to demonstrate the effectiveness of antiviral therapy in combatting HCC. The study provides a compelling rationale for incorporating antiviral therapy into the management of HBV/HCV-related HCC, offering patients a fighting chance against this formidable disease.

Date :
  1. Date Completed 2010-09-20
  2. Date Revised 2022-03-21
Further Info :

Pubmed ID

20556841

DOI: Digital Object Identifier

PMC2887591

SNS
PICO Info
in preparation
Languages

English

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