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The effect of perindopril and hydrochlorothiazide alone and in combination on blood pressure and on the renin-angiotensin system in hypertensive subjects.
Author: BackhouseC I, BrownC L, GrippatJ C, SantoniJ P
Original Abstract of the Article :
The pharmacodynamic effects and acceptability of perindopril (4 mg daily) and hydrochlorothiazide (25 mg daily) given alone or in combination for 1 month were investigated in a double-blind, placebo controlled, parallel group study. The pharmacokinetics of perindopril and its active metabolite perin...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
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引用元:
https://doi.org/10.1007/BF00315404
データ提供:米国国立医学図書館(NLM)
Evaluating the Effects of Perindopril and Hydrochlorothiazide on Blood Pressure
This study investigates the effects of two different medications, perindopril and hydrochlorothiazide, on blood pressure in patients with hypertension. It explores the individual and combined effects of these medications on blood pressure levels and the renin-angiotensin system. This research is essential for optimizing blood pressure control in patients with hypertension.Finding the Right Path to Lower Blood Pressure
The study found that both perindopril and hydrochlorothiazide effectively lowered blood pressure, either alone or in combination. The combined effect was additive for diastolic blood pressure and synergistic for systolic blood pressure. This research provides valuable insights into the different approaches to managing blood pressure in hypertensive patients. It's like finding a variety of paths through the desert, each offering a unique way to reach the oasis of lower blood pressure.Managing Blood Pressure: A Desert Journey
This research reminds us that there are many ways to navigate the desert of high blood pressure. It's important to work with your doctor to find the best treatment plan for your individual needs. Remember, healthy lifestyle choices, such as exercise and diet, can also contribute to lower blood pressure levels.Dr.Camel's Conclusion
This study provides a comprehensive evaluation of the effects of perindopril and hydrochlorothiazide on blood pressure, highlighting the importance of individualized treatment approaches for managing hypertension. It's a reminder that even in the vast desert of cardiovascular health, there are always new discoveries and tools to improve our well-being.Date :
- Date Completed 1991-04-23
- Date Revised 2019-08-13
Further Info :
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PICO Info
in preparation
Languages
English
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