Paper Details
- Home
- Paper Details
Excellent tolerability but relatively low initial clinical efficacy of telcagepant in migraine.
Author: Tfelt-HansenPeer
Original Abstract of the Article :
In 3 randomized clinical trials (n = 1585) the calcitonin gene-related peptide antagonist telcagepant 300 mg orally had an incidence of adverse events similar to placebo when used in the acute treatment of migraine. Telcagepant, thus, has excellent tolerability in migraine. Only a quarter (26%) (334...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1111/j.1526-4610.2010.01797.x
データ提供:米国国立医学図書館(NLM)
Telcagepant: A Promising but Incomplete Solution for Migraine
The world of headache medicine is always seeking new solutions to alleviate the debilitating pain and disability caused by migraine. This study, published in [Journal name], investigated the effectiveness of telcagepant, a calcitonin gene-related peptide antagonist, in the acute treatment of migraine. Three randomized clinical trials involving 1585 patients were analyzed.Telcagepant: Well-Tolerated but Variable Efficacy
While telcagepant was found to be well-tolerated, with an adverse event profile similar to placebo, its efficacy in achieving pain freedom was relatively low. Only 26% of patients achieved pain freedom after 2 hours, compared to 56% who experienced pain relief. While this study suggests that telcagepant holds promise as a migraine treatment, further research is needed to improve its efficacy and identify patients who may benefit most.Exploring the Desert of Migraine Treatment
Migraine treatment is a journey through a complex and often frustrating desert landscape. This study provides a valuable map, highlighting the potential of telcagepant but also revealing its limitations. Further research is needed to optimize the use of telcagepant and discover new treatments that can offer a more complete solution for those suffering from migraine.Dr.Camel's Conclusion
The search for effective migraine treatment is like navigating a vast and arid desert, often leaving sufferers feeling lost and parched. This study offers a glimpse of a potential oasis, with telcagepant showing promise but needing further development. Like a camel seeking the most fertile patch of desert, researchers continue their journey in search of the ultimate solution for migraine pain.Date :
- Date Completed 2011-04-25
- Date Revised 2018-12-01
Further Info :
Related Literature
Article Analysis
SNS
PICO Info
in preparation
Languages
English
Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.
This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.