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ABH gel is not absorbed from the skin of normal volunteers.
Author: CoynePatrick J, DodsonPatricia, FletcherDevon, ParkerGwendolyn, PoklisJustin L, RitterJoseph K, SmithThomas J
Original Abstract of the Article :
Lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), haloperidol (Haldol(®)) (ABH) topical gel is currently widely used for nausea in hospice because of perceived efficacy and low cost and has been suggested for cancer chemotherapy. However, there are no studies of absorption, a prerequisite for ef...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1016/j.jpainsymman.2011.05.017
データ提供:米国国立医学図書館(NLM)
Exploring the Desert of Absorption: A Study of Topical Medications
This research, like a camel caravan traversing a vast and often mysterious desert, delves into the world of topical medications, specifically focusing on the absorption of a gel containing lorazepam, diphenhydramine, and haloperidol (ABH gel). The researchers, like skilled explorers venturing into uncharted territory, are seeking to understand whether the drugs in this gel are absorbed through the skin, a crucial factor in determining its effectiveness. The study, like a compass guiding a traveler through a complex landscape, investigates the absorption of ABH gel in healthy volunteers, carefully analyzing their skin to determine the extent of drug penetration. Their findings, like a well-mapped oasis, reveal that ABH gel drugs are not absorbed through the skin, challenging the assumptions about its potential efficacy.Navigating the Desert of Topical Medication: A Journey of Uncertainty
This study, like a camel caravan navigating a vast and sometimes treacherous desert, explores the absorption of a topical gel containing lorazepam, diphenhydramine, and haloperidol. The researchers' findings, like a well-mapped oasis, reveal that these drugs are not absorbed through the skin, questioning the validity of previous assumptions about its efficacy. This research underscores the importance of rigorous scientific investigation, like a skilled desert navigator relying on accurate maps and data, to ensure the safety and effectiveness of topical medications.Exploring the Desert of Medication Safety: A Reminder to Stay Informed
This study, like a camel caravan venturing into a vast and often uncharted desert, reminds us of the importance of rigorous scientific investigation to ensure the safety and effectiveness of medications. The researchers' findings highlight the need for careful evaluation, like a skilled desert navigator relying on accurate maps and data, to understand the true impact of medications, especially those applied topically. This research underscores the importance of staying informed about medication absorption and efficacy, like a wise camel navigating a treacherous landscape with caution and knowledge.Dr. Camel's Conclusion
This study, like a camel caravan traversing a vast and often mysterious desert, explores the absorption of a topical gel containing lorazepam, diphenhydramine, and haloperidol. The researchers' findings, like a well-mapped oasis, reveal that these drugs are not absorbed through the skin, questioning the validity of previous assumptions about its efficacy. This research underscores the importance of rigorous scientific investigation to ensure the safety and effectiveness of medications, especially those applied topically.Date :
- Date Completed 2012-09-17
- Date Revised 2013-11-21
Further Info :
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