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Partial oral treatment of endocarditis.

Author: BruunNiels Eske, BundgaardHenning, ChristensenJens Jørgen, ElmingHanne, FuurstedKurt, GillSabine, HassagerChristian, Holst-HansenClaus, HøfstenDan, HøstNis, IhlemannNikolaj, IversenKasper, KorupEva, LarsenJannik Helweg, MoserClaus, PumpBettina, RosenvingeFlemming, SchønheyderHenrik Carl, WiggersHenrik

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Current guidelines recommend giving antibiotics through a vein (intravenously) for 4-6 weeks to treat left-sided infective endocarditis (IE). Switching to oral antibiotics in patients who are stable could reduce side effects and hospital stays. While there's limited evidence, some observations suggest that this approach might be safe and effective.
Paper Details　
Original Abstract of the Article :
Guidelines for the treatment of left-sided infective endocarditis (IE) recommend 4 to 6 weeks of intravenous antibiotics. Conversion from intravenous to oral antibiotics in clinically stabilized patients could reduce the side effects associated with intravenous treatment and shorten the length of ho...See full text at original site
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引用元：
https://doi.org/10.1016/j.ahj.2012.11.006

データ提供：米国国立医学図書館（NLM）

Partial Oral Treatment of Endocarditis: A New Path in the Desert of Infection

Endocarditis, an infection of the inner lining of the heart, is a serious condition that often requires prolonged intravenous antibiotic therapy. This review explores the potential of partial oral treatment, transitioning from intravenous to oral antibiotics in clinically stabilized patients, as a safer and more convenient alternative. The researchers examined the available evidence for the effectiveness and safety of this approach.

A Shifting Sands Approach to Treatment

Partial oral therapy for endocarditis offers a potential shift in the traditional treatment landscape. Observational data suggest that this strategy may be safe and effective, potentially reducing side effects and shortening hospital stays. However, further research is needed to confirm these findings and establish clear guidelines for its use.

Navigating the Desert of Treatment Options

This review highlights the ongoing search for innovative and patient-centered approaches to endocarditis management. As we navigate the complexities of infection and treatment, it is crucial to explore options that optimize outcomes while minimizing the burden on patients.

Dr. Camel's Conclusion

Partial oral treatment for endocarditis presents a potential new path in the desert of infection, offering a more convenient and potentially less burdensome option for patients. Further research is essential to pave the way for wider adoption of this promising approach.

Date :
  1. Date Completed 2013-03-21
  2. Date Revised 2013-01-28
Further Info :

Pubmed ID

23351813

DOI: Digital Object Identifier

10.1016/j.ahj.2012.11.006

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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