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Comparison of effects of 5 and 10 mg oral desloratadine and levocetirizine on histamine-induced wheal and flare response in healthy volunteers.
Author: BayramgürlerDilek, BilenNilgün, BulcaSongül, KıranRebiay, Odyakmaz DemirsoyEvren, Sikar AktürkAysun, YavuzMelike
Original Abstract of the Article :
BACKGROUND: Levocetirizine and desloratadine are mostly used as H1-antihistamines in the treatment of allergic disease in 5 and 10 mg doses. OBJECTIVE: In this study, the efficacy of single oral dosages of 5 and 10 mg desloratadine and levocetirizine were compared by using histamine-induced wheal a...See full text at original site
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引用元:
https://doi.org/10.3109/09546634.2013.777152
データ提供:米国国立医学図書館(NLM)
A Head-to-Head Showdown: Desloratadine vs. Levocetirizine
Allergic reactions can be a nuisance, and finding the right antihistamine to alleviate symptoms is often a trial-and-error process. This study delves into the comparative efficacy of desloratadine and levocetirizine, two commonly used H1-antihistamines, in blocking histamine-induced wheal and flare reactions. The researchers aimed to assess the effectiveness of both drugs at different doses, providing valuable insights for patients seeking relief from allergic symptoms.
Levocetirizine Emerges as the Winner
The study demonstrated that levocetirizine, at both 5 mg and 10 mg doses, was more effective in suppressing histamine-induced wheal and flare reactions compared to desloratadine. This finding suggests that levocetirizine may be a more potent option for individuals seeking relief from allergic symptoms. The researchers also observed a dose-dependent effect of levocetirizine, with the 10 mg dose providing more sustained relief than the 5 mg dose.
Finding the Right Antihistamine for You
This research offers valuable information for individuals seeking relief from allergic reactions. While levocetirizine emerged as the more effective antihistamine in this study, it's crucial to remember that individual responses to medications can vary. Consulting with a healthcare professional is essential to determine the best treatment approach for your specific needs and to discuss any potential side effects or interactions with other medications.
Dr.Camel's Conclusion
Just as a desert traveler seeks a cool breeze, allergy sufferers seek relief from itchy, watery eyes and a stuffy nose. This research provides a compass for navigating the world of antihistamines, highlighting the potential benefits of levocetirizine. Remember, finding the right medication and managing your allergies is like finding a hidden oasis in the vast desert of symptoms - it requires patience, guidance, and a bit of trial and error.
Date :
- Date Completed 2014-04-04
- Date Revised 2022-04-08
Further Info :
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