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Tolerance and biological activity of pentosan polysulfate after intramuscular or subcutaneous administration for ten days in human volunteers.
Author: AlbaredeJ L, BoneuB, BoulouxC, ChigotC, CorrellS, LansenJ, RobertM, SiéP, ThouvenotJ P
Original Abstract of the Article :
This study reports on the tolerance and the pharmacological activity of pentosan polysulfate (PPS) administered to healthy volunteers for 10 days. Three groups of 10 subjects received either one daily injections of 100 mg of PPS by I. M. route (group I), or two daily injection of 50 mg of PPS by I. ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
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難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://pubmed.ncbi.nlm.nih.gov/2422778
データ提供:米国国立医学図書館(NLM)
Pentosan Polysulfate: Tolerance and Pharmacological Activity in Humans
This research, published in [Journal Name], explores the safety and effectiveness of pentosan polysulfate (PPS) when administered to healthy volunteers. This study involved three groups of volunteers who received different doses and routes of PPS administration for ten days. The study measured the tolerance and pharmacological activity of PPS, providing insights into its potential therapeutic applications.
Safety and Efficacy of Pentosan Polysulfate
The results of this study show that PPS is generally well-tolerated, with most side effects being mild and manageable. The researchers noted potential effects on liver enzymes and platelet counts, which require further investigation. They found that PPS exhibited a pharmacological activity that could potentially be beneficial for certain medical conditions.
Implications for Potential Therapies
The findings from this study provide valuable information about the safety and efficacy of PPS. This knowledge can inform the development of potential therapies for conditions that may benefit from PPS's pharmacological properties. Further research is needed to explore the potential benefits and risks of PPS in a wider range of patients and settings.
Dr.Camel's Conclusion
Think of PPS like a desert oasis - it's a potential source of relief and healing, but careful observation and assessment are necessary to ensure its safe and effective use. This research helps us understand the properties of PPS, allowing us to explore its potential benefits while remaining aware of its potential side effects.
Date :
- Date Completed 1986-05-30
- Date Revised 2006-11-15
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English
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