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[Perindopril: first-line treatment of arterial hypertension].

Author: DescheP, ZanchettiA

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
English AbstractA summary of a research paper/publication written in English for a wider audience.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Perindopril (P) was compared to captopril (C), atenolol (A), and a combined diuretic (D) in treating essential hypertension. P was equally effective as C and A in monotherapy, and more effective than C and A when combined with a diuretic. P was less effective than D when combined with a beta-blocker. Overall, P was well-tolerated and effective in controlling hypertension.
Paper Details　
Original Abstract of the Article :
The effectiveness and acceptability of perindopril (P) as an antihypertensive agent were compared with those of captopril (C), atenolol (A) and a combined hydrochlorothiazide + amiloride diuretic (D) in three simultaneous multicentre double-blind trials involving 165, 173 ans 165 patients respective...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2505715

データ提供：米国国立医学図書館（NLM）

Perindopril: A First-Line Treatment for High Blood Pressure

High blood pressure is a major health concern, affecting millions of people worldwide. It's like a constant pressure building up inside a balloon, threatening to burst if not properly managed. This study investigates the effectiveness of perindopril, a drug used to treat hypertension, compared to other commonly used antihypertensive medications. It's like comparing different camel caravans to see which one is best equipped to cross the desert of hypertension.

Perindopril: A Reliable Companion on the Journey to Lower Blood Pressure

The study found that perindopril was as effective as other antihypertensive medications in controlling blood pressure. It also demonstrated a good safety profile, with minimal side effects. It's like having a strong and reliable camel that can carry you across the desert without any major hiccups. These findings suggest that perindopril is a valuable first-line treatment option for hypertension.

Choosing the Right Camel: Finding the Best Hypertension Treatment

This study provides valuable insights into the effectiveness and safety of perindopril for hypertension. It's a reminder that there are multiple treatment options available, and finding the best one for each individual patient is crucial. It's like choosing the right camel for your journey across the desert - some camels are better suited for certain terrains and weather conditions than others. The study highlights the importance of personalized treatment plans and careful consideration of individual patient needs.

Dr. Camel's Conclusion

This study confirms the effectiveness and safety of perindopril as a first-line treatment for hypertension. It's a testament to the ongoing efforts to develop safe and effective medications to manage this common health condition. It's like finding a reliable oasis in the desert of hypertension, offering a source of relief and hope for millions of people around the world.
Date :
  1. Date Completed 1989-10-06
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2505715

DOI: Digital Object Identifier

2505715

SNS
PICO Info
in preparation
Languages

French

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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