Failure in longterm treatment is rare in actively treated patients with rheumatoid arthritis, but may be predicted by high health assessment score at baseline and by residual disease activity at 3 and 6 months: the 5-year followup results of the randomized clinical NEO-RACo trial.

Author: , HannonenPekka, JärvenpääSalme, Kaipiainen-SeppänenOili, KarjalainenAnna, KautiainenHannu, KorpelaMarkku, Leirisalo-RepoMarjatta, MalmiTimo, MustilaAnu, MöttönenTimo, PaimelaLeena, RantalaihoVappu, UutelaToini, Yli-KerttulaTimo

Paper Details 
Original Abstract of the Article :
With modern initial aggressive combination treatments with synthetic disease-modifying antirheumatic drugs (sDMARD), most patients with rheumatoid arthritis (RA) achieve remission, have marginal radiographic progression, and sustain normal function. Here we aim to identify the patients failing these...See full text at original site
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引用元:
https://doi.org/10.3899/jrheum.140267

データ提供:米国国立医学図書館(NLM)

Rheumatoid Arthritis: A Long Journey to Remission

Rheumatoid arthritis (RA) is a chronic inflammatory disease that can significantly impact joint health and quality of life. This study investigated the long-term outcomes of actively treated patients with RA, evaluating factors associated with treatment failure. The researchers analyzed data from a 5-year follow-up study, revealing that while most patients achieved remission with aggressive combination therapy, a subset of patients experienced treatment failure. The study identified two key predictors of treatment failure: a high health assessment score at baseline and residual disease activity at 3 and 6 months.

Identifying the Roadblocks to Remission

This research provides a deeper understanding of the challenges associated with managing RA. The study's findings highlight the importance of early intervention and aggressive treatment to achieve long-term remission. This is like navigating a desert with a clear map, ensuring that you are on the right path and heading towards your destination. By identifying key predictors of treatment failure, healthcare providers can tailor treatment strategies to maximize the chances of achieving long-term remission.

A Personalized Approach to RA Management

This research underscores the importance of a personalized approach to RA management, considering individual factors and disease activity over time. The study's findings suggest that patients with higher baseline health assessment scores and residual disease activity at 3 and 6 months may require more intensive monitoring and tailored treatment strategies to achieve long-term remission. This is like customizing your camel to suit the specific challenges of the desert landscape. By tailoring treatment plans to individual needs, healthcare providers can optimize outcomes and improve the quality of life for RA patients.

Dr. Camel's Conclusion

This study highlights the complexity of managing RA and the importance of a personalized approach to treatment. The researchers' findings underscore the need for early intervention, aggressive therapy, and close monitoring to achieve long-term remission. It's a reminder that the journey to remission can be long and challenging, but with the right strategies and support, patients can navigate the desert of RA and reach a more fulfilling life. Just like a camel traversing the vast desert, it's important to be adaptable and resilient, adjusting to the changing landscape of the disease and seeking guidance along the way.

Date :
  1. Date Completed 2015-08-18
  2. Date Revised 2016-11-25
Further Info :

Pubmed ID

25274892

DOI: Digital Object Identifier

10.3899/jrheum.140267

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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