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Long-Term Outcomes of Patients With Recent-Onset Rheumatoid Arthritis After 10 Years of Tight Controlled Treatment: A Randomized Trial.

Author: AkdemirGülsah, AllaartCornelia F, DirvenLinda, Goekoop-RuitermanYvonne P M, HanK Huub, HuizingaTom W J, KerstensPit J S M, Le CessieSaskia, LemsWillem F, MarkusseIris M, MolenaarT H Esmeralda, PeetersAndré J, RondayH Karel, SpeyerIrene, StijnenTheo, Ten WoldeSaskia, de SonnavillePeter B J, van GroenendaelJohannes H L M, van der LubbePeter A H M

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

Initial combination therapy in patients with early rheumatoid arthritis resulted in faster clinical improvement, and targeted treatment determined long-term outcomes, with a 53% remission rate and a 14% drug-free remission rate after 10 years.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Treat-to-target therapy is effective for patients with rheumatoid arthritis (RA), but long-term results of continued targeted treatment are lacking. OBJECTIVE: To evaluate long-term outcomes in patients with early RA after 10 years of targeted treatment in 4 treatment strategies. DESIG...See full text at original site
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引用元：
https://doi.org/10.7326/M15-0919

データ提供：米国国立医学図書館（NLM）

Long-Term Rheumatoid Arthritis Treatment: A Ten-Year Journey Across the Desert

Rheumatoid arthritis (RA) is a chronic inflammatory condition that can feel like traversing a harsh desert of pain and inflammation. This research delves into the long-term effects of different treatment strategies for RA, examining their impact on functional ability, radiographic progression, and overall survival. Researchers are interested in understanding how to optimize treatment plans for patients with RA, enabling them to navigate the challenges of the disease and maintain a good quality of life over the long term.

Navigating the Desert of Rheumatoid Arthritis

The study's findings demonstrate the importance of early and aggressive treatment for RA. It's like a camel caravan leader choosing the best route through a challenging desert. The research suggests that targeting treatment to achieve low disease activity can significantly improve long-term outcomes, minimizing functional deterioration and radiographic damage.

Finding Hope in the Desert of Chronic Illness

This research offers a beacon of hope for individuals with RA, demonstrating that a proactive approach to treatment can lead to positive long-term outcomes. It's like discovering a hidden oasis in the middle of a desert – offering a chance for relief and sustained well-being. The findings underscore the importance of working closely with healthcare providers to develop personalized treatment plans that address the unique needs of each patient.

Dr. Camel's Conclusion

This study reveals the power of early and aggressive treatment in managing rheumatoid arthritis. It's like finding a reliable camel caravan to guide you through the desert of chronic illness, ensuring a more comfortable and fulfilling journey.

Date :
  1. Date Completed 2016-08-29
  2. Date Revised 2022-04-08
Further Info :

Pubmed ID

27089068

DOI: Digital Object Identifier

10.7326/M15-0919

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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