A double-blind, randomized, placebo-controlled trial of combined calcitriol and ergocalciferol versus ergocalciferol alone in chronic kidney disease with proteinuria.

Author: Eiam-OngSomchai, KatavetinPisut, NakwanSiriwan, PeerapornratanaSadudee, PraditpornsilpaKearkiat, SrisawatNattachai, SusantitaphongPaweena, TiranathanagulKhajohn

Paper Details 
Original Abstract of the Article :
KDOQI guideline suggests that nutritional vitamin D should be supplemented in chronic kidney disease (CKD) patients who have vitamin D insufficiency/deficiency. However, there are scarce data regarding the additional benefit of active vitamin D supplement in CKD patients who were receiving nutrition...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5237567/

データ提供:米国国立医学図書館(NLM)

Exploring the benefits of combined calcitriol and ergocalciferol in chronic kidney disease

The field of chronic kidney disease (CKD) is a vast and challenging desert, with researchers constantly seeking new oases of effective therapies. This study, like a camel caravan exploring this terrain, investigates the potential benefits of adding active vitamin D (calcitriol) to nutritional vitamin D (ergocalciferol) supplementation in CKD patients with proteinuria. The researchers examined the effects of this combined therapy on proteinuria and kidney function, searching for a more effective way to manage this challenging condition.

The study suggests a potential for optimizing vitamin D supplementation in CKD patients

The study's findings, like a shimmering oasis in a parched desert, suggest that adding active vitamin D to nutritional vitamin D supplementation might offer additional benefits for CKD patients with proteinuria. This is like discovering a new source of water in a desolate land, offering a potential path toward better management of this complex condition.

Implications for chronic kidney disease management and patient care

The study's findings highlight the importance of individualized approaches to managing CKD, recognizing that each patient is like a unique desert landscape with its own set of needs. It underscores the need for careful consideration of vitamin D supplementation strategies and the potential benefits of combining different forms of vitamin D to optimize patient outcomes. This is like tailoring a caravan's route to navigate the diverse terrain of the desert, ensuring a safe and successful journey.

Dr.Camel's Conclusion

This study, like a beacon of hope in the vast desert of CKD research, suggests that combining calcitriol and ergocalciferol might offer additional benefits for patients with proteinuria. It underscores the importance of individualized approaches to vitamin D supplementation, like tailoring a caravan's supplies to the specific needs of the journey.

Date :
  1. Date Completed 2017-11-21
  2. Date Revised 2018-11-13
Further Info :

Pubmed ID

28088187

DOI: Digital Object Identifier

PMC5237567

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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