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Adverse effects of oral antiviral therapy in chronic hepatitis B.

Author: GunerRahmet, KayaaslanBircan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Oral nucleoside/nucleotide analogues (NAs) are commonly used to treat chronic hepatitis B (CHB) infection. They are generally safe and well tolerated, but can cause side effects such as myopathy, neuropathy, and lactic acidosis. All NAs have a "Black Box" warning due to the risk of mitochondrial dysfunction, though this is rarely reported. This review provides an update on the adverse effects of oral NAs, including the specific risks associated with different drugs.
Paper Details　
Original Abstract of the Article :
Oral nucleoside/nucleotide analogues (NAs) are currently the backbone of chronic hepatitis B (CHB) infection treatment. They are generally well-tolerated by patients and safe to use. To date, a significant number of patients have been treated with NAs. Safety data has accumulated over the years. The...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316843/

データ提供：米国国立医学図書館（NLM）

Oral Antiviral Therapy for Chronic Hepatitis B: A Balancing Act

This research explores the world of [chronic hepatitis B (CHB)] and the use of [oral nucleoside/nucleotide analogues (NAs)] to manage this condition. It's like navigating a desert; while [NAs] offer a potential oasis, they also come with potential risks. The authors comprehensively review the [adverse effects] associated with [NAs], highlighting the importance of balancing their [therapeutic benefits] with their [potential risks]. The study emphasizes the need for [ongoing monitoring] to ensure the safe and effective use of these medications.

Navigating the Desert of Chronic Hepatitis B

The study's findings provide valuable guidance for clinicians managing patients with [CHB]. It's like navigating a vast desert; we must be aware of the potential challenges and seek optimal pathways for treatment. The study underscores the importance of [individualized treatment plans] tailored to the specific needs of each patient, considering both the [benefits and risks] of [NAs] therapy.

Protecting Our Health: A Journey of Awareness

This research emphasizes the importance of being informed about the [potential risks and benefits] of medications. It's like a camel caravan traversing a desert; we must be aware of potential dangers and prepare accordingly. The study highlights the need for [open communication] between patients and healthcare providers to ensure [safe and effective treatment] for chronic hepatitis B.

Dr.Camel's Conclusion

This research, like a wise camel, reminds us that while medications can offer relief, they also come with potential side effects. The study sheds light on the complex interplay between [oral antiviral therapy] and [chronic hepatitis B]. By understanding the potential risks and benefits, we can navigate the desert of this condition with greater awareness and care.

Date :
  1. Date Completed n.d.
  2. Date Revised 2020-09-30
Further Info :

Pubmed ID

28261380

DOI: Digital Object Identifier

PMC5316843

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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