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Effects of theophylline on behavior and learning in children with asthma.

Author: CoffmanH, DeGrawC, FentonT, GuareR, RappaportL, TwarogF

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Theophylline had no significant effects on behavior, attention, memory, or fine motor function in children with asthma. However, parents and children reported more stomachaches and shaking hands when taking theophylline.
Paper Details　
Original Abstract of the Article :
This study examined the potential side effects of theophylline on behavior, attention, memory, and fine motor function in children with asthma. Seventeen children of normal intelligence who were intermittent theophylline users were recruited. Each was not taking medication at the initiation of the s...See full text at original site
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引用元：
https://doi.org/10.1001/archpedi.1989.02150150126032

データ提供：米国国立医学図書館（NLM）

Theophylline and Behavior in Children with Asthma: A Double-Blind Crossover Study

This research examines the potential behavioral side effects of [theophylline], a commonly used medication for [asthma] in children. The study utilized a [double-blind crossover design] to investigate the effects of theophylline on behavior, attention, memory, and fine motor function in 17 children with asthma.

Navigating the Desert of Side Effects: Theophylline and Cognitive Function

The researchers found that while some analyses suggested a possible improvement in memory while taking theophylline, other tests showed no significant effect. Parents and children reported more stomachaches and shaking hands while on theophylline. However, the study did not reveal any significant behavioral side effects overall.

Finding Balance in the Desert: Theophylline and Asthma Treatment

This research suggests that theophylline, while a common medication for asthma, may not have the same impact on behavior in every child. This highlights the importance of individualizing treatment and carefully monitoring for potential side effects, especially when managing medications that can affect both physical and cognitive functions.

Dr.Camel's Conclusion

This study reminds us that even a seemingly common medication can have diverse effects on different individuals. It is like traversing a desert with a map that may not always accurately reflect the landscape. We must remain vigilant in our approach to treatment, always seeking the most appropriate path for each patient.

Date :
  1. Date Completed 1989-03-23
  2. Date Revised 2019-07-16
Further Info :

Pubmed ID

2916514

DOI: Digital Object Identifier

10.1001/archpedi.1989.02150150126032

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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