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High-versus low-dose, frequently administered, nebulized albuterol in children with severe, acute asthma.

Author: CannyG, HealyR, LevisonH, ParkinP, RajanA, RiederM, SchuhS, SoldinS J, TanY K

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

High-dose nebulized albuterol was effective in treating severe, acute asthma in children. There were no significant differences in side effects between the high and low dose groups.
Paper Details　
Original Abstract of the Article :
Thirty-two 5- to 17-year-old children who had severe, acute asthma were randomly assigned to receive either high doses (0.15 mg/kg of body weight per dose) or low doses (0.05 mg/kg of body weight per dose) of nebulized albuterol every 20 minutes for six doses. Compared with the low-dose regimen, the...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/2927990

データ提供：米国国立医学図書館（NLM）

High-Dose Albuterol: A Rescue Mission in the Desert of Severe Asthma

Severe asthma, a formidable sandstorm in the desert of respiratory health, can leave individuals gasping for breath. This research, like a daring expedition seeking a cure, investigated the effectiveness of high-dose nebulized albuterol in children experiencing severe, acute asthma attacks. The researchers, like skilled desert navigators, compared the effects of high-dose and low-dose albuterol regimens, searching for the optimal approach to alleviate respiratory distress. The study, like a beacon of hope in the desert, revealed that the high-dose regimen resulted in significantly greater improvement in lung function and a lower hospitalization rate.

A Breath of Fresh Air: High-Dose Albuterol's Positive Impact

This research, like a wellspring in the arid desert, offers hope for children struggling with severe asthma attacks. The study demonstrated that high-dose nebulized albuterol, administered frequently, significantly improved lung function and reduced the need for hospitalization. This finding could potentially lead to better management of acute asthma episodes and improved quality of life for children with this condition.

Navigating the Desert of Asthma: A Balanced Approach

While the high-dose albuterol regimen proved effective, it's crucial to acknowledge the potential side effects of this medication. Like a desert traveler who needs to balance hydration and energy expenditure, healthcare professionals must carefully weigh the benefits and risks of using high-dose albuterol, ensuring personalized care for each patient.

Dr.Camel's Conclusion

This research, a testament to the ongoing quest for better asthma treatments, sheds light on the potential benefits of high-dose nebulized albuterol in managing severe, acute asthma attacks in children. The study's findings, like a desert oasis providing respite from the harsh environment, offer hope for improved outcomes and a better quality of life for children with this condition. However, it's important to approach asthma management with a balanced perspective, considering the individual needs and potential side effects of each treatment option.

Date :
  1. Date Completed 1989-04-28
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

2927990

DOI: Digital Object Identifier

2927990

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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