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Clinical experience with aztreonam in Europe: a summary of studies in Belgium, England, Finland, Ireland, the Netherlands, Norway, Portugal, and Sweden.

Author: NorrbyS R

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the effectiveness of aztreonam in treating various bacterial infections in 342 patients. Aztreonam was highly effective for treating urinary tract infections, with a 91.5% success rate. It was also effective for pneumonia, with an 86% success rate. The drug was successful in eliminating most bacterial strains, including Pseudomonas aeruginosa. Side effects were rare and only led to one patient stopping treatment. However, four seriously ill patients developed staphylococcal infections and died. The study recommends using aztreonam in combination with other antibiotics for infections other than urinary tract infections.
Paper Details　
Original Abstract of the Article :
Therapeutic results are given for 342 patients treated with various doses of aztreonam in 20 studies. One hundred sixty-five patients had urinary tract infections; 40 of these patients were bacteremic. Favorable clinical response was reported for 91.5% of the patients, and only one bacteremic patien...See full text at original site
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引用元：
https://doi.org/10.1093/clinids/7.supplement_4.s836

データ提供：米国国立医学図書館（NLM）

Clinical Experience with Aztreonam in Europe

This study analyzes the effectiveness and safety of aztreonam, an antibiotic used to treat various infections. Imagine a bustling marketplace where different 'bacteria' are competing for space. Aztreonam is like a skilled merchant who can effectively eliminate certain types of 'bacteria', specifically gram-negative bacteria, from the market. The study reviewed 20 studies involving 342 patients who were treated with aztreonam, finding it to be effective against various infections, particularly urinary tract infections and pneumonia. The drug showed excellent efficacy and a relatively low incidence of adverse reactions, making it a valuable tool for treating these infections.

Aztreonam: A Powerful Weapon in the Fight Against Infections

The study demonstrates the effectiveness of aztreonam in treating various infections. Its efficacy and safety profile make it a valuable addition to the arsenal of antibiotics used to combat bacterial infections. It's like a camel equipped with a powerful shield and a keen eye, able to protect itself from potential threats in the desert.

Protecting Ourselves from the Desert's Bacteria

This study emphasizes the importance of developing effective antibiotics to combat infections. By understanding the mechanisms of bacterial resistance and developing new drugs, scientists are continuously working to protect us from the 'bacteria' lurking in the 'desert' of our bodies. Like a camel that adapts to its environment, we must stay vigilant and seek appropriate medical attention when necessary.

Dr. Camel's Conclusion

This study highlights the importance of continued research and innovation in the field of antibiotic development. By staying ahead of bacterial resistance and developing new therapies, we can protect ourselves from the constant threat of infection. Just like a camel navigating the desert, we must be prepared for the challenges ahead and be ready to adapt our strategies to overcome them.

Date :
  1. Date Completed 1986-02-19
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

2934788

DOI: Digital Object Identifier

10.1093/clinids/7.supplement_4.s836

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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