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Effects of meclofenamate and acetaminophen on abdominal pain following tubal occlusion.

Author: CaissieK F, HuangK C, SimpsonP M, TsuedaK, WolfeW M

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Meclofenamate was more effective than acetaminophen in reducing postoperative abdominal pain after tubal occlusion. It also provided substantial analgesia for 4 hours.
Paper Details　
Original Abstract of the Article :
To test the hypothesis that the postoperative abdominal pain of tubal occlusion is mediated by prostaglandins, the effects of meclofenamate, a potent inhibitor of cyclooxygenase, on postoperative analgesia and incidence of abdominal pain were compared with those of acetaminophen, a weak inhibitor of...See full text at original site
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引用元：
https://doi.org/10.1016/0002-9378(86)90291-7

データ提供：米国国立医学図書館（NLM）

Postoperative Pain Relief: Exploring the Desert of Prostaglandins

This study investigates the role of prostaglandins in postoperative abdominal pain after tubal occlusion. It's like exploring the desert's ecosystem to understand the role of different elements in causing discomfort. The researchers compared the effects of meclofenamate, a potent inhibitor of cyclooxygenase, with acetaminophen, a weaker inhibitor. They found that both drugs provided pain relief, but meclofenamate was significantly more effective in reducing the incidence of abdominal pain, suggesting that prostaglandins play a significant role in this type of postoperative pain.

Prostaglandins and Pain: A Key to the Desert's Secrets

The study highlights the importance of understanding the underlying mechanisms of pain. It's like studying the desert's landscape to understand the factors that contribute to its unique characteristics. The researchers' findings suggest that prostaglandins, a group of lipids involved in various bodily processes, may be a key factor in postoperative abdominal pain. This knowledge can lead to more effective pain management strategies.

Reducing Postoperative Pain: A More Comfortable Desert Journey

The study's findings suggest that meclofenamate, a potent inhibitor of prostaglandins, could be a valuable tool for managing postoperative abdominal pain after tubal occlusion. It's like having a reliable camel for a comfortable journey through the desert. This research contributes to a better understanding of pain mechanisms, leading to more effective treatments that can improve patient comfort and recovery.

Dr.Camel's Conclusion

The desert of pain can be a challenging landscape, but understanding its mechanisms can lead to effective treatments. This study highlights the role of prostaglandins in postoperative abdominal pain, emphasizing the need for effective pain management strategies. By understanding the desert's ecosystem, we can find ways to reduce discomfort and improve patient outcomes.

Date :
  1. Date Completed 1986-10-23
  2. Date Revised 2019-06-15
Further Info :

Pubmed ID

2944386

DOI: Digital Object Identifier

10.1016/0002-9378(86)90291-7

SNS
PICO Info
in preparation
Languages

English

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