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Comparison of the antihypertensive effects of celiprolol and acebutolol.

Author: BelovezhdovN, GerovaZ, TerziivanovD, VlahovV

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Celiprolol and acebutolol, two cardioselective beta-blockers, were compared for their antihypertensive effects. Both drugs showed comparable efficacy in reducing blood pressure, but celiprolol showed a stronger correlation between blood pressure reduction and its plasma concentration.
Paper Details　
Original Abstract of the Article :
The antihypertensive effects of the new cardioselective beta-blocker celiprolol and acebutolol have been compared. Thirty patients with arterial hypertension WHO Grade I-II were treated in a double-blind fashion with celiprolol or acebutolol. Before starting the treatment and on Days 15 and 29, befo...See full text at original site
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引用元：
https://doi.org/10.1007/BF00614547

データ提供：米国国立医学図書館（NLM）

A Race to the Finish Line: Comparing Antihypertensive Medications

This study takes us into the realm of [Cardiology] and explores the effectiveness of two beta-blockers, celiprolol and acebutolol, in managing hypertension. The researchers used a double-blind study design, akin to a blindfolded race where both participants strive for the same goal - lowering blood pressure. The researchers sought to determine if one medication was more effective than the other in achieving this crucial goal.

A Tie for the Winner: Equally Effective Medications

The study demonstrates that both celiprolol and acebutolol effectively lower blood pressure, with no significant difference in their efficacy. This finding highlights the importance of individualizing treatment based on patient characteristics and preferences. It's like having two equally capable camels for a desert journey, each with their own strengths and weaknesses. The key is to choose the right camel for the specific terrain and the individual's needs.

A Journey to Lower Blood Pressure: Finding the Right Medication

This study emphasizes the importance of working closely with healthcare providers to find the best medication for managing hypertension. It’s a reminder that managing blood pressure is an ongoing journey, and finding the right tools and strategies can make a significant difference in overall health and well-being. It's like navigating a desert landscape, where the right map and supplies can make the journey smoother and more successful.

Dr. Camel's Conclusion

This study highlights the importance of individualized care in managing hypertension. It’s a reminder that there’s no one-size-fits-all approach to medication, and finding the right tool for the job is crucial. It's like selecting the right camel for a desert journey, ensuring the right fit for a safe and successful journey to a healthier life.

Date :
  1. Date Completed 1988-07-29
  2. Date Revised 2019-08-13
Further Info :

Pubmed ID

2968268

DOI: Digital Object Identifier

10.1007/BF00614547

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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