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The place of gliclazide MR in the evolving type 2 diabetes landscape: A comparison with other sulfonylureas and newer oral antihyperglycemic agents.

Author: ChanSiew Pheng, ColagiuriStephen, LeiterLawrence A, MarreMichel, MatthewsDavid, SestiGiorgio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

Sulfonylureas are effective oral glucose-lowering agents, but their pharmacokinetic properties differ, leading to variations in hypoglycemia, cardiovascular, and renal safety. This review compares sulfonylureas, focusing on gliclazide MR's advantages, including high glucose-lowering efficacy, once-daily administration, few side effects (except mild hypoglycemia), and cardiovascular safety.
Paper Details　
Original Abstract of the Article :
The sulfonylureas are effective oral glucose-lowering agents with a long history of clinical use. While all have the same general mechanism of action, their pharmacokinetic properties are influenced by factors such as dosage, rate of absorption, duration of action, route of elimination, tissue speci...See full text at original site
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引用元：
https://doi.org/10.1016/j.diabres.2018.05.028

データ提供：米国国立医学図書館（NLM）

Gliclazide MR: A Promising Sulfonylurea in the Evolving Type 2 Diabetes Landscape

Type 2 diabetes is a growing global health concern, requiring effective and safe treatment options. This research examines the place of gliclazide modified release (MR) in the evolving landscape of type 2 diabetes management, comparing it to other sulfonylureas and newer oral antihyperglycemic agents. It's like a camel caravan exploring a vast desert of therapeutic options, seeking the most effective and sustainable route to manage diabetes.

Gliclazide MR: A Powerful Tool in the Fight Against Type 2 Diabetes

The study highlights the effectiveness of gliclazide MR in lowering HbA1c levels, a key indicator of blood glucose control. It also emphasizes the safety profile of gliclazide MR, particularly regarding cardiovascular and renal effects. It's like finding a reliable and safe oasis in the desert, providing sustained nourishment and support for those managing diabetes.

Navigating the Complexities of Type 2 Diabetes Management

This research emphasizes the importance of considering a range of treatment options for type 2 diabetes, taking into account individual patient characteristics and preferences. It highlights the need for personalized care and ongoing monitoring to ensure optimal outcomes. It's like selecting the right camel for a specific desert journey, ensuring the most comfortable and effective approach to managing diabetes.

Dr.Camel's Conclusion

This research provides valuable insights into the effectiveness and safety of gliclazide MR as a treatment option for type 2 diabetes. By carefully considering the individual needs of patients and navigating the complex landscape of diabetes management, healthcare professionals can optimize treatment strategies and ensure better outcomes for their patients. It's like a camel caravan embarking on a journey through a challenging desert, equipped with the knowledge and resources to overcome obstacles and reach a healthier destination.

Date :
  1. Date Completed 2018-11-05
  2. Date Revised 2018-11-05
Further Info :

Pubmed ID

29802958

DOI: Digital Object Identifier

10.1016/j.diabres.2018.05.028

SNS
PICO Info
in preparation
Languages

English

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