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Opioid Misuse as a Predictor of Alcohol Treatment Outcomes in the COMBINE Study: Mediation by Medication Adherence.

Author: KranzlerHenry R, VotawVictoria R, VowlesKevin E, WitkiewitzKatie

Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Opioid misuse and other drug use were associated with poorer AUD treatment outcomes. Opioid misuse significantly predicted the time to first heavy drinking day and a higher probability of being in a heavier and more frequent drinking profile at the end of treatment and at 1 year following treatment.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Alcohol is often consumed with opioids and alcohol misuse interferes with treatment for opioid use disorder (OUD). Drug misuse is associated with worse alcohol use disorder (AUD) treatment outcomes, yet no studies have investigated the role of opioid misuse in AUD treatment outcomes. ME...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/29873089

データ提供：米国国立医学図書館（NLM）

Opioid Misuse and Alcohol Treatment: A Complex Relationship

The misuse of opioids, a class of drugs used to relieve pain, is a growing public health concern. This research explores the impact of opioid misuse on the outcomes of alcohol use disorder (AUD) treatment. The researchers analyzed data from a large clinical trial of medications and behavioral interventions for AUD. They found that individuals with opioid misuse were more likely to experience poorer treatment outcomes, including earlier relapses to drinking, higher frequency of drinking, and increased drinking intensity.

Opioid Misuse: A Hidden Influence on Alcohol Treatment

This study underscores the importance of considering opioid misuse when treating AUD. Opioid misuse can have a significant impact on treatment outcomes, and it's crucial for healthcare providers to assess and address this factor. Imagine a camel trying to navigate a desert filled with hidden traps. These traps, like opioid misuse, can hinder progress and lead to setbacks.

Addressing Opioid Misuse: A Crucial Step in Alcohol Treatment

This research highlights the need for a comprehensive approach to AUD treatment that addresses not only alcohol use but also other substance use disorders, particularly opioid misuse. Treatment plans should be tailored to the individual patient's needs and consider the potential impact of opioid misuse on treatment outcomes.

Dr.Camel's Conclusion

This study reveals the complex relationship between opioid misuse and alcohol treatment. It's essential for healthcare providers to be aware of this connection and to address opioid misuse in patients undergoing AUD treatment. By understanding the full picture of substance use, we can develop more effective treatment strategies and help individuals achieve lasting recovery.

Date :
  1. Date Completed 2019-09-25
  2. Date Revised 2023-09-26
Further Info :

Pubmed ID

29873089

DOI: Digital Object Identifier

NIHMS968624

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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