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Partial Oral versus Intravenous Antibiotic Treatment of Endocarditis.

Author: BruunNiels E, BundgaardHenning, ChristensenJens J, ElmingHanne, FosbøllEmil L, FurstedKurt, GillSabine U, Helweg-LarsenJannik, HøfstenDan E, IhlemannNikolaj, IversenKasper, JensenKaare T, KleinChristine F, KøberLars, MadsenTrine, MoserClaus, RosenvingeFlemming, SchultzMartin, SchønheyderHenrik C, Torp-PedersenChristian, TønderNiels

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Equivalence TrialA clinical trial designed to show that a new treatment is equivalent in efficacy/safety to an existing treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

People with a heart infection (infective endocarditis) on the left side of the heart are usually treated with intravenous antibiotics for up to six weeks. It's unclear if switching to oral antibiotics once the patient is stable would be as effective and safe as continuing intravenous treatment.
Paper Details　
Original Abstract of the Article :
Patients with infective endocarditis on the left side of the heart are typically treated with intravenous antibiotic agents for up to 6 weeks. Whether a shift from intravenous to oral antibiotics once the patient is in stable condition would result in efficacy and safety similar to those with contin...See full text at original site
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引用元：
https://doi.org/10.1056/NEJMoa1808312

データ提供：米国国立医学図書館（NLM）

Oral vs. Intravenous Antibiotics for Endocarditis: A Desert of Uncertainty

Infective endocarditis, an infection of the heart's inner lining, is like a treacherous journey through a desert of bacteria. This study investigates the effectiveness of shifting from intravenous to oral antibiotic treatment for endocarditis, exploring whether this transition can provide safe and effective management for patients. It's like searching for a safe passageway through the desert, hoping to find a path that allows for a smoother and more comfortable journey towards recovery.

The researchers aim to determine if shifting from intravenous to oral antibiotics once a patient with left-sided endocarditis is stable can achieve similar efficacy and safety compared to continued intravenous treatment. They are seeking to find a bridge across the desert, allowing for a transition to a more manageable and convenient treatment approach.

A New Path to Recovery

This study aims to find a new path through the desert of endocarditis treatment, exploring the potential for a safe and effective transition from intravenous to oral antibiotics. The research is like searching for a new caravan route that can provide a more comfortable and efficient way to navigate the challenges of this challenging infection.

Navigating the Desert of Infection

Understanding the most effective and safe treatment strategies for endocarditis is essential for improving patient outcomes. This study, like a compass in the desert, is guiding researchers towards a better understanding of the nuances of endocarditis treatment.

Dr.Camel's Conclusion

This study, like a journey through a desert of uncertainty, seeks to determine the best path for managing endocarditis. The quest for a safe and effective transition from intravenous to oral antibiotics continues, offering hope for a smoother and more comfortable journey towards recovery.

Date :
  1. Date Completed 2019-02-08
  2. Date Revised 2022-04-09
Further Info :

Pubmed ID

30152252

DOI: Digital Object Identifier

10.1056/NEJMoa1808312

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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