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Human papillomavirus infection: protocol for a randomised controlled trial of imiquimod cream (5%) versus podophyllotoxin cream (0.15%), in combination with quadrivalent human papillomavirus or control vaccination in the treatment and prevention of recurrence of anogenital warts (HIPvac trial).

Author: BennettKate, CopasAndrew J, DoréCaroline J, GilsonRichard, HaddowLewis J, JitMark, LaceyCharles, MeadowsJade, MurrayMacey L, NathanMayura, SoldanKate, TetlowMichelle

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Anogenital warts are a common sexually transmitted infection. About 90% are caused by HPV types 6 and 11, and half of cases are recurrences. The best treatment for anogenital warts is unclear. Common treatments include topical medications like podophyllotoxin or imiquimod, and freezing (cryotherapy). While the HPV vaccine prevents infection, it's unclear if it can also treat existing warts.
Paper Details　
Original Abstract of the Article :
Anogenital warts are the second most common sexually transmitted infection diagnosed in sexual health services in England. About 90% of genital warts are caused by human papillomavirus (HPV) types 6 or 11, and half of episodes diagnosed are recurrences. The best and most cost-effective treatment for...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220496/

データ提供：米国国立医学図書館（NLM）

Anogenital Warts: A Persistent Desert Challenge

Anogenital warts, a common sexually transmitted infection, can cause discomfort and social stigma. This study investigates the effectiveness of different treatment modalities for anogenital warts, including topical agents, cryotherapy, and vaccination. Think of it as navigating a desert filled with thorny bushes, seeking ways to protect yourself and heal any wounds.

A Comprehensive Approach to Treatment

The study explores the potential of various treatment options for anogenital warts, including imiquimod cream, podophyllotoxin cream, and quadrivalent HPV vaccination. This is like having a diverse toolkit for navigating the desert, with different tools suited for different tasks. The study also emphasizes the importance of preventing recurrences, highlighting the need for long-term management strategies.

Navigating the Desert of Infection: Prevention and Treatment

This research provides valuable insights into the management of anogenital warts, offering hope for those seeking effective treatment and prevention strategies. It's like having a guide who can teach you how to avoid thorny bushes and heal any wounds you may encounter. By understanding the different treatment options and their associated risks and benefits, patients and healthcare providers can work together to navigate this challenging health issue.

Dr. Camel's Conclusion

This study highlights the importance of comprehensive and personalized approaches to treating and preventing anogenital warts. It's like having a team of explorers working together, sharing their knowledge and resources to overcome a common challenge. By utilizing a combination of treatment modalities and promoting preventive measures, we can help individuals navigate this health issue and minimize its impact on their lives.
Date :
  1. Date Completed 2019-08-12
  2. Date Revised 2019-08-12
Further Info :

Pubmed ID

30400777

DOI: Digital Object Identifier

PMC6220496

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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