A Critical Review of Nebivolol and its Fixed-Dose Combinations in the Treatment of Hypertension.

Author: BorghiClaudio, CiceroArrigo F G, KuwabaraMasanari

Paper Details 
Original Abstract of the Article :
β-Adrenergic receptor blockers (β-blockers) are well-known useful and cost-effective drugs for managing hypertensive patients with coronary heart disease, stroke, and heart failure. However, it is often difficult to use β-blockers for patients with asthma or chronic obstructive pulmonary disease (CO...See full text at original site
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引用元:
https://doi.org/10.1007/s40265-018-0999-y

データ提供:米国国立医学図書館(NLM)

Nebivolol: A Promising Option for Managing Hypertension

Hypertension, or high blood pressure, is a common and serious health condition that can lead to heart disease, stroke, and other complications. Beta-blockers are a class of medications commonly used to treat hypertension. However, some beta-blockers can have negative side effects, such as affecting glucose or lipid metabolism. This research explores the benefits and limitations of nebivolol, a third-generation beta-blocker with unique properties.

Nebivolol is a beta-1 receptor-selective blocker with nitric oxide-mediated vasodilatory effects. This unique combination of properties makes it a potentially better choice for patients with asthma or COPD, who may not tolerate other beta-blockers. Nebivolol also has a neutral effect on glucose and lipid metabolism. This review summarizes the clinical studies on nebivolol and its use in combination with other antihypertensive drugs.

The review found that nebivolol is generally well-tolerated and effective in lowering blood pressure. It also found that fixed-dose combinations of nebivolol with other antihypertensive drugs may be a useful option for patients who require multiple medications to manage their hypertension.

The Importance of Choosing the Right Medication for Hypertension

This research highlights the importance of choosing the right medication for hypertension. Nebivolol's unique properties make it a potentially better choice for certain patients than other beta-blockers. This review provides valuable information that can help clinicians make informed decisions about treatment for hypertension.

Optimizing Hypertension Management

This research underscores the need for personalized approaches to hypertension management. Nebivolol's unique properties and the availability of fixed-dose combinations with other antihypertensive drugs offer clinicians a wider range of options for optimizing hypertension management. This personalized approach can help to improve patient outcomes and minimize side effects.

Dr.Camel's Conclusion

This research is like a treasure map guiding us through the desert of hypertension management. By understanding the unique properties of nebivolol and its fixed-dose combinations, we can find the most effective and safe treatment options for our patients. It's a reminder that we must always strive to find the best possible solutions for each individual, just as a skilled desert explorer would carefully navigate the landscape to reach their destination.

Date :
  1. Date Completed 2019-07-31
  2. Date Revised 2019-07-31
Further Info :

Pubmed ID

30426333

DOI: Digital Object Identifier

10.1007/s40265-018-0999-y

SNS
PICO Info
in preparation
Languages

English

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