[Treatment of essential mild-to-moderate arterial hypertension with once-daily penbutolol. Controlled clinical study vs atenolol].

Author: BianchiniC, GennariC, MartinelliM, NamiR

Paper Details 
Original Abstract of the Article :
The anti-hypertensive and tolerance of penbutolol, a non-selective beta-blocker of long duration and endowed with an ISA effect were compared with those of atenolol, a cardioselective beta-blocker without ISA effect, in two groups of 20 patients each suffering from slight-to-moderate essential prima...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/3059235

データ提供:米国国立医学図書館(NLM)

A Tale of Two Beta-Blockers: A Clinical Trial in the Desert of Hypertension

Hypertension, or high blood pressure, is a common condition, like the endless expanse of the desert. Researchers are always striving to find the best ways to manage this condition, and this study compares the effectiveness of two beta-blockers, penbutolol and atenolol, in treating mild-to-moderate essential hypertension. The authors conducted a randomized, controlled clinical trial, carefully selecting patients with similar characteristics. They studied the anti-hypertensive effects of each drug, as well as their tolerability. This research is akin to meticulously exploring the desert, comparing different paths to find the most effective route.

Navigating the Desert of Hypertension

The study found that both penbutolol and atenolol effectively reduced blood pressure, reaching their peak effect within the second week of treatment. Interestingly, penbutolol demonstrated better tolerability than atenolol. This research sheds light on the potential for personalized treatment strategies, allowing physicians to choose the best drug based on individual patient needs. These findings are like discovering a new oasis, offering more options for managing hypertension.

A Healthier Desert: Managing Hypertension

High blood pressure is a major risk factor for heart disease and stroke, both of which can have devastating consequences. This study highlights the importance of managing hypertension effectively, which can lead to improved heart health. The findings suggest that penbutolol may be a more suitable option for some patients due to its improved tolerability. By understanding the nuances of different treatments, we can create a healthier desert, promoting well-being for all.

Dr. Camel's Conclusion

This research is a reminder that even in the seemingly endless expanse of the desert of hypertension, there are always new discoveries to be made. The comparison of penbutolol and atenolol offers valuable insights into the potential for personalized treatment strategies, allowing physicians to choose the best course of action for each patient. As we continue to explore this complex condition, we are constantly seeking to find better ways to navigate the desert of hypertension and create a healthier future for all.

Date :
  1. Date Completed 1989-01-26
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3059235

DOI: Digital Object Identifier

3059235

SNS
PICO Info
in preparation
Languages

Italian

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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