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Hydrochlorothizide-induced acute generalised exanthematous pustulosis presenting with bilateral periorbital impetigo.

Author: LariosJose, MarshallMichael, ReapLeo E, RoddCassandra

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Hydrochlorothiazide, a diuretic, has been reported to induce acute generalised exanthematous pustulosis (AGEP) in two cases, highlighting the need for caution when using this drug.
Paper Details　
Original Abstract of the Article :
Acute generalised exanthematous pustulosis (AGEP) is a severe cutaneous adverse reaction characterised by the appearance of erythematous plaques and papules with overlying non-follicular pinpoint pustules. Drugs are the cause of AGEP in approximately 90% of cases. The most common causes include anti...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381958/

データ提供：米国国立医学図書館（NLM）

A Rare Case of Hydrochlorothiazide-Induced Acute Generalised Exanthematous Pustulosis

This case report presents a rare instance of acute generalized exanthematous pustulosis (AGEP) induced by hydrochlorothiazide, a commonly used diuretic. The case highlights the importance of recognizing AGEP as a potential adverse drug reaction, particularly in patients receiving hydrochlorothiazide.

The Uncommon Link between Hydrochlorothiazide and AGEP

This case report sheds light on the uncommon connection between hydrochlorothiazide and AGEP, a severe skin reaction characterized by widespread pustules.

The Many Faces of Drug Reactions

Imagine the body as a vast desert landscape, where even seemingly innocuous substances can trigger unexpected reactions. This case report explores the unpredictable nature of drug reactions, showcasing the potential for seemingly harmless medications like hydrochlorothiazide to cause severe skin reactions like AGEP. This story serves as a reminder for clinicians to be vigilant in monitoring patients for potential adverse drug reactions, particularly those receiving medications with known side effects.

Dr.Camel's Conclusion

This case report highlights the importance of recognizing acute generalized exanthematous pustulosis (AGEP) as a potential adverse drug reaction to hydrochlorothiazide. The case underscores the importance of vigilant monitoring for potential drug reactions, particularly in patients receiving commonly used medications like diuretics.
Date :
  1. Date Completed 2019-05-20
  2. Date Revised 2021-02-11
Further Info :

Pubmed ID

30755424

DOI: Digital Object Identifier

PMC6381958

SNS
PICO Info
in preparation
Languages

English

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