Effects of long-term maintenance therapy with a new glucocorticoid, deflazacort, on mineral metabolism and statural growth.

Author: BalsanS, BourdeauA, GrimbergR, LenoirG, StéruD

Paper Details 
Original Abstract of the Article :
Deflazacort was substituted for Prednisone (based on the equivalence 1 mg Prednisone equals 1.2 mg Deflazacort), during maintenance glucocorticoid therapy in 9 children, 5 with renal diseases and 4 with connective tissue or immunoproliferative disorders. Six patients received 0.26-0.35 mg/kg body we...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1007/BF02556690

データ提供:米国国立医学図書館(NLM)

A New Glucocorticoid for Pediatric Growth

The world of pediatrics is always searching for ways to effectively manage chronic diseases while minimizing the impact on a child's growth and development. This study delves into the intriguing realm of deflazacort, a new glucocorticoid, examining its potential benefits in the treatment of children with various conditions, including renal diseases and connective tissue disorders. This research, like a determined explorer charting a path through a vast desert, aims to understand the long-term effects of this new treatment.

Positive Growth, Minimal Side Effects

The results are promising. Deflazacort demonstrated excellent therapeutic effects while significantly reducing or eliminating the undesirable side effects commonly associated with traditional glucocorticoids. It's like discovering a hidden oasis in the desert, offering both healing and rejuvenation. The study found that deflazacort had minimal impact on mineral metabolism and even led to a modest acceleration in growth velocity for some children.

Hope for a Brighter Future

These findings hold tremendous hope for children with chronic illnesses, offering a potential treatment that can both manage their condition and minimize the negative impact on their growth. It's like finding a sustainable source of water in a barren landscape, offering a brighter future for the children and their families.

Dr.Camel's Conclusion

Deflazacort's potential to provide effective treatment with minimal side effects and even promote growth is a significant discovery. It's like discovering a new species of cactus that thrives in the harshest conditions, offering a unique and valuable solution.

Date :
  1. Date Completed 1987-08-31
  2. Date Revised 2019-08-28
Further Info :

Pubmed ID

3111667

DOI: Digital Object Identifier

10.1007/BF02556690

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.