Paper Details

  1. Home
  2. Paper Details

Lamivudine vs placebo or no treatment in preventing the transmission of hepatitis B virus during pregnancy: a systematic review and meta-analysis.

Author: BaiXiaoxia, QianXueqian, SuChang, YangXiaofu, ZhaoPeng

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Hepatitis B virus (HBV) infection is a major health concern, especially in developing countries, where nearly half the population lives in areas with high rates of transmission. The most common way HBV spreads is from mother to child. While antiviral treatments are available, their effectiveness is still being debated.
Paper Details　
Original Abstract of the Article :
Hepatitis B virus (HBV) infection is a severe health problem, especially in developing countries. Almost 45% of the population lives in highly endemic areas, where the most common form of transmission is mother to child transmission (MTCT). Administration of antiviral therapy has been established. N...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1093/trstmh/trz078

データ提供：米国国立医学図書館（NLM）

Preventing Hepatitis B Virus Transmission During Pregnancy: A Challenging Journey

Hepatitis B virus (HBV) infection is a global health concern, particularly in developing countries. Mother-to-child transmission (MTCT) is a significant pathway for HBV transmission, and this study delves into the potential of lamivudine, an antiviral medication, in preventing this transmission during pregnancy. The researchers conducted a systematic review and meta-analysis of available evidence, examining the efficacy of lamivudine compared to placebo or no treatment.

Lamivudine's Role: A Potential Oasis in the Desert of HBV Transmission

The meta-analysis suggests that lamivudine may be effective in preventing HBV transmission during pregnancy. However, the authors acknowledge that the evidence is limited and more research is needed to solidify these findings.

Navigating the Desert of HBV Transmission

The desert of HBV transmission is a complex landscape with many challenges. This study offers hope for preventing MTCT, but more research is needed to fully understand the effectiveness and safety of lamivudine in this context. Early diagnosis and treatment are crucial to minimizing the risk of transmission.

Dr. Camel's Conclusion

This study ventures into the vast desert of HBV transmission during pregnancy, offering insights into the potential benefits of lamivudine as a preventative measure. While the evidence is promising, further research is needed to solidify these findings and ensure the safety of this intervention. Like a camel navigating a challenging terrain, healthcare professionals must continue to explore and innovate to protect mothers and their children from the dangers of HBV transmission.

Date :
  1. Date Completed 2021-06-02
  2. Date Revised 2021-06-02
Further Info :

Pubmed ID

31703121

DOI: Digital Object Identifier

10.1093/trstmh/trz078

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.