Effects of Weekly Supplementation of Cholecalciferol and Calcifediol Among the Oldest-Old People: Findings From a Randomized Pragmatic Clinical Trial.

Author: AntinolfiPierluigi, BaroniMarta, BiniVittorio, BoccardiVirginia, BrozzettiAnnalisa, FalorniAlberto, LapennaMaria, MecocciPatrizia, ParrettiLuca, RuggieroCarmelinda, ZengariniElisa

Paper Details 
Original Abstract of the Article :
Vitamin D inadequacy is pervasive in the oldest-old. Many vitamin D metabolites are available for supplementation, their effects on the recovery of adequate serum levels remain unknown. We investigate the effects of supplementation with cholecalciferol (D3) and calcifediol (25D3) on serum levels of ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893743/

データ提供:米国国立医学図書館(NLM)

Vitamin D Supplementation for the Oldest-Old: A Quest for Optimal Levels

The journey of aging is a unique and complex one, often marked by changes in health and well-being. This study explores the effects of vitamin D supplementation on the oldest-old, those who are 80 years of age and older. Vitamin D plays a crucial role in maintaining bone health and immune function, and its deficiency is common in older adults. This is like finding a hidden spring in the desert, offering a potential solution to the challenges of aging.

Finding the Right Dose

The study found that both cholecalciferol (D3) and calcifediol (25D3) supplementation significantly increased vitamin D serum levels in the oldest-old individuals. However, calcifediol demonstrated a faster recovery of acceptable parathyroid hormone levels. This is like choosing the right type of camel for a long journey, one that can navigate the desert terrain with greater efficiency. The study also identified polypharmacy and low muscle strength as factors that can hinder the effectiveness of vitamin D supplementation. This is like encountering obstacles in the desert landscape, requiring a change in strategy to overcome challenges.

Navigating Vitamin D Supplementation in the Oldest-Old

This research provides valuable insights into the optimal approach to vitamin D supplementation for the oldest-old. It highlights the importance of considering individual factors, such as polypharmacy and muscle strength, when determining the appropriate dosage and type of supplementation. This is like carefully assessing the terrain of the desert before embarking on a journey, ensuring that the traveler is well-equipped to face any challenges. The study underscores the importance of personalized care and ongoing monitoring to optimize vitamin D levels and support the health of older adults.

Dr.Camel's Conclusion

This study explores the effects of vitamin D supplementation on the oldest-old, offering valuable insights into the optimal approach to maintaining adequate vitamin D levels in this population. It highlights the importance of considering individual factors, such as polypharmacy and muscle strength, when determining the appropriate dosage and type of supplementation. Just like a wise camel navigating the desert, healthcare providers must remain vigilant in monitoring and managing the health of older adults, ensuring their well-being and supporting them on their journey through life.

Date :
  1. Date Completed 2020-05-08
  2. Date Revised 2020-05-08
Further Info :

Pubmed ID

31731651

DOI: Digital Object Identifier

PMC6893743

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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