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Quantification of Adverse Drug Reactions Related to Drug Switches in The Netherlands.
Author: BurgerDavid M, GlerumPieter J, MaliepaardMarc, NeefKees, SchollJoep H G, de ValkVincent, van HunselFlorence P A M, van PuijenbroekEugène P
Original Abstract of the Article :
We performed a retrospective cohort study in the Dutch patient population to identify active substances with a relatively high number of adverse drug reactions (ADRs) potentially related to drug switching. For this, we analyzed drug switches and reported ADRs related to switching between June 1, 200...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7214643/
データ提供:米国国立医学図書館(NLM)
Drug Switches and Adverse Drug Reactions: A Closer Look
Adverse drug reactions (ADRs) are a significant concern in healthcare, with drug switching often contributing to this issue. This research investigates the occurrence of ADRs potentially related to drug switches in The Netherlands. The study aimed to identify active substances with a relatively high number of ADRs associated with switching, using data from the National Health Care Institute and Lareb, The Netherlands Pharmacovigilance Centre. The findings provide valuable insights into the pharmacovigilance of drug switching and highlight the need for careful monitoring of ADRs related to this practice.
Rivastigmine, Levothyroxine, Methylphenidate, and Salbutamol: Notable Drug Switches
The study identified four active substances with relatively high numbers of ADRs per 100,000 switches: rivastigmine, levothyroxine, methylphenidate, and salbutamol. This research emphasizes the importance of recognizing the potential risks associated with drug switching, particularly for these specific substances. The study’s findings highlight the need for increased vigilance and monitoring of ADRs related to drug switching to ensure patient safety and minimize potential risks.
Navigating the Desert of Drug Interactions
The world of drug interactions can be as complex and vast as a desert. This research sheds light on the importance of understanding the potential risks associated with drug switches. It emphasizes the need for careful monitoring and analysis of ADRs related to these changes. This study encourages healthcare professionals to be mindful of the potential impact of drug switching on patient safety and to carefully consider the risks and benefits before making such changes.
Dr.Camel's Conclusion
The study is a valuable reminder that the landscape of drug interactions is complex and requires careful navigation. It highlights the importance of vigilant monitoring of ADRs related to drug switching, especially for certain active substances. This research provides a roadmap for ensuring patient safety and mitigating potential risks associated with drug switching. Let’s continue to explore and enhance our understanding of drug interactions to optimize patient care and promote overall health and well-being.
Date :
- Date Completed 2021-08-06
- Date Revised 2021-08-06
Further Info :
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