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The cardiovascular safety of antiobesity drugs-analysis of signals in the FDA Adverse Event Report System Database.
Author: GorelikBoris, GorelikEinat, Hirsh-RaccahBruria, MasarwaReem, MatokIlan, PerlmanAmichai
Original Abstract of the Article :
AIMS: Over the past several decades, many antiobesity drugs have been withdrawn from the market due to unanticipated adverse events, often involving cardiotoxicity. This study aimed to evaluate the presence of cardiovascular safety signals with currently marketed antiobesity drugs. METHODS: We used...See full text at original site
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引用元:
https://doi.org/10.1038/s41366-020-0544-4
データ提供:米国国立医学図書館(NLM)
Navigating the Sands of Antiobesity Drug Safety: A Look at Cardiovascular Risks
The quest for [effective antiobesity drugs] is fraught with challenges. Many promising drugs have been withdrawn from the market due to [unforeseen adverse events], particularly those related to [cardiotoxicity]. This study delves into the [cardiovascular safety] of currently marketed [antiobesity drugs], examining potential signals of [cardiovascular risk] using a vast and complex dataset from the [US Food and Drug Administration Adverse Event Reporting System (FAERS)], much like an adventurous desert explorer sifting through the grains of sand to uncover hidden treasures.
Cardiovascular Signals in the Sands of Antiobesity Drug Data
The study's findings indicate a potential signal for [valvular disorders] with [lorcaserin], while no significant signals were detected for other [cardiovascular events] with the other [antiobesity drugs] examined. These findings are a reminder of the ongoing need for vigilance in monitoring the safety of [antiobesity drugs], much like a camel caravan must constantly be aware of its surroundings in a vast and unforgiving desert.
A Call for Further Research: Navigating the Uncertainties of Antiobesity Drug Safety
The study underscores the importance of [ongoing surveillance] for [cardiovascular safety] signals with [antiobesity drugs]. Further research is necessary to confirm the findings regarding [lorcaserin] and to better understand the [long-term cardiovascular effects] of all [antiobesity drugs]. The journey of [weight management] is challenging enough, and it's essential to ensure that the tools we use are safe and effective. Just as a desert traveler needs to choose the safest route, patients and physicians must carefully consider the risks and benefits of [antiobesity drugs] to navigate the complex landscape of [weight management] safely.
Dr. Camel's Conclusion
This study provides valuable insights into the potential [cardiovascular risks] associated with [antiobesity drugs]. It underscores the importance of ongoing [safety monitoring] and highlights the need for further research to better understand the potential [side effects] of these drugs. As we continue to explore the vast and challenging desert of [weight management], it's essential to navigate carefully and make informed decisions based on the best available evidence.
Date :
- Date Completed 2021-09-06
- Date Revised 2021-09-06
Further Info :
English
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