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Lamotrigine add-on therapy for drug-resistant focal epilepsy.

Author: BresnahanRebecca, MarsonAnthony G, PanebiancoMariangela, RamaratnamSridharan

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This review looks at the use of lamotrigine, an anti-seizure medication, as an additional treatment for epilepsy that doesn't respond well to other medications. While lamotrigine can reduce seizures, it can also have side effects. This updated review provides new information on lamotrigine's effectiveness and potential side effects.
Paper Details　
Original Abstract of the Article :
This is an updated version of the Cochrane Review previously published in 2016. Epilepsy is a common neurological disorder, affecting 0.5% to 1% of the population. For nearly 30% of these people, their epilepsy is resistant to currently available drugs. Pharmacological treatment remains the first ch...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7083514/

データ提供：米国国立医学図書館（NLM）

Lamotrigine: A Potential Solution for Drug-Resistant Epilepsy

Epilepsy is a challenging neurological disorder that affects millions around the world. It’s like a desert storm that can disrupt the lives of those who experience it. This study examines the efficacy of lamotrigine, a newer antiepileptic drug, as an add-on therapy for drug-resistant focal epilepsy.

Lamotrigine: A Promising Add-on Therapy

The research shows that lamotrigine, when combined with other antiepileptic drugs, can significantly reduce seizures in patients who have not responded well to conventional treatments. However, it’s important to note that lamotrigine can also cause side effects, which is like a sandstorm that can accompany a desert adventure. The study emphasizes the need to carefully monitor and manage these potential side effects.

Hope for Improved Epilepsy Management

This research presents a promising avenue for improving the management of drug-resistant epilepsy. Lamotrigine provides a new weapon in the fight against this debilitating condition.

Dr.Camel's Conclusion

The discovery of lamotrigine as an effective add-on therapy for drug-resistant epilepsy is like finding a way to tame a desert storm. This treatment offers a glimmer of hope for those struggling with this challenging condition. It’s important to remember that the journey to managing epilepsy can be difficult, but with continued research and innovation, we can continue to improve the lives of those affected by this disorder.

Date :
  1. Date Completed 2020-07-31
  2. Date Revised 2022-09-14
Further Info :

Pubmed ID

32196639

DOI: Digital Object Identifier

PMC7083514

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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