Paper Details

  1. Home
  2. Paper Details

[A parallel comparative double blind study of cefixime with cefaclor in the treatment of acute suppurative otitis media in children].

Author: BabaS, ItohY, KawamuraS, KinoshitaH, KobayashiK, MoriY, OnishiS, ShimadaJ, SuzukiK, UedaR

English AbstractA summary of a research paper/publication written in English for a wider audience.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Cefixime (CFIX) was as effective as cefaclor (CCL) in treating acute suppurative otitis media in children. CFIX was significantly superior to CCL in eradicating bacteria (97.1% vs 90.3%, P<.05) and improving individual symptoms. Both drugs were well tolerated.
Paper Details　
Original Abstract of the Article :
A double blind study was carried out to compare the efficacy and safety of cefixime (CFIX), a new oral cephem with cefaclor (CCL) in the treatment of 245 children weighing 10 approximately 30 kg, with acute suppurative otitis media. The daily dosages of CFIX and CCL were 3 approximately 6 mg/kg in 2...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/3295321

データ提供：米国国立医学図書館（NLM）

Cefixime vs. Cefaclor: A Race Through the Desert of Otitis Media

Acute suppurative otitis media (ASOM), a common infection affecting young children, is like a sandstorm that can quickly bring discomfort and pain. The authors of this study compared the efficacy and safety of two antibiotics, cefixime and cefaclor, in treating ASOM in children. They conducted a double-blind study to determine which drug offered the most effective and safe treatment option for this debilitating condition.

Cefixime Shows Promise in Treating Otitis Media

The study found that cefixime demonstrated superior efficacy compared to cefaclor in treating ASOM in children. The eradication rates of bacteria were significantly higher in the cefixime group compared to the cefaclor group, and cefixime also showed improvement in individual symptoms like redness of the tympanic membrane and purulent secretion. Both drugs had a good safety profile, with no significant difference in side effects.

Finding the Right Antibiotics for Children with Otitis Media

The study suggests that cefixime could be a valuable treatment option for ASOM in children. Its higher eradication rate and superior symptom improvement make it a promising alternative to cefaclor. As with all antibiotics, it's crucial to consult with a healthcare professional to determine the most appropriate treatment for each child based on their individual circumstances.

Dr. Camel's Conclusion

Navigating the desert of childhood infections is a constant challenge. This study provides valuable insights into the treatment of ASOM, suggesting that cefixime may be a more effective option compared to cefaclor. Like finding a wellspring of fresh water in a parched landscape, identifying the right antibiotic for our little ones is crucial for ensuring their health and well-being.

Date :
  1. Date Completed 1987-07-14
  2. Date Revised 2016-11-16
Further Info :

Pubmed ID

3295321

DOI: Digital Object Identifier

3295321

SNS
PICO Info
in preparation
Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.