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EORTC trial non-Hodgkin lymphomas.

Author: BurgersJ M, DuezN, HayatM, QasimM, SomersR, Van GlabbekeM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A study of 468 patients with non-Hodgkin lymphoma found that treatment effectiveness varied based on stage and histological subtype. Maintenance chemotherapy after regional radiotherapy did not significantly improve survival for stage I patients but did improve disease-free survival. Chemotherapy regimens for stage III and IV patients did not differ in effectiveness, and patients with follicular lymphoma had better long-term outcomes.
Paper Details　
Original Abstract of the Article :
Results of an EORTC trial (20751) in non-Hodgkin lymphomas are presented. Patients were treated in the same way independent of the histological type. There were 468 patients in the study of whom 124 patients were in stage I (85% 5 year survival), 57 in stage II (55%), 121 in stage III (55%) and 166 ...See full text at original site
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引用元：
https://doi.org/10.1016/0277-5379(87)90072-1

データ提供：米国国立医学図書館（NLM）

EORTC Trial for Non-Hodgkin Lymphomas: A Journey Through the Desert of Cancer Treatment

The battle against non-Hodgkin lymphoma (NHL) is a journey through a vast and often unforgiving desert. This study, like a camel traversing the sands of cancer treatment research, explores the results of an EORTC (European Organisation for Research and Treatment of Cancer) trial for NHL patients. The researchers aimed to evaluate the effectiveness of different treatment strategies for NHL, seeking to improve outcomes for patients battling this challenging disease.

Navigating the Desert of Treatment: EORTC's Findings

The researchers, like skilled desert navigators, analyzed data from a large cohort of NHL patients who participated in the EORTC trial. They found that treatment outcomes varied depending on the stage of the disease and the histological type of NHL. They discovered that patients with low-grade lymphomas, especially those with a follicular pattern, had a better prognosis compared to those with high-grade lymphomas. This finding, like a shimmering oasis, offers valuable insights into the complexities of NHL treatment.

A Desert Oasis of Hope: Improving Outcomes for NHL Patients

This study, like a well-equipped caravan, provides valuable insights into the treatment of NHL. The researchers discovered that treatment outcomes are influenced by the stage of the disease and the histological type of NHL. They also found that maintenance chemotherapy could improve disease-free survival for patients with stage I NHL. This research, like a cool spring in the desert, offers hope for those battling this challenging disease.

Dr. Camel's Conclusion

The fight against NHL is a journey through a vast and often unforgiving desert. This study, like a camel carrying a precious load of knowledge, helps us better understand the complexities of this disease and the importance of personalized treatment strategies. The EORTC trial, like a well-mapped caravan route, has provided valuable insights into the best approaches for managing NHL, paving the way for new and improved treatments that offer hope for patients facing this challenge.

Date :
  1. Date Completed 1987-08-13
  2. Date Revised 2019-09-08
Further Info :

Pubmed ID

3297719

DOI: Digital Object Identifier

10.1016/0277-5379(87)90072-1

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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