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Oral Fabrol (oral N-acetyl-cysteine) in chronic bronchitis.

Author: HuitsonA, ParrG D

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study investigated the effectiveness of N-acetylcysteine (NAC) in reducing exacerbations (worsening of symptoms) in 526 patients with chronic bronchitis. Patients were randomly assigned to receive either NAC or placebo for six months. The study found no significant difference in the number of exacerbations between the two groups. However, patients taking NAC had fewer days of incapacitation due to their symptoms. The study concludes that while NAC may not reduce the number of exacerbations, it can improve the overall experience for patients with chronic bronchitis.
Paper Details　
Original Abstract of the Article :
Five hundred and twenty-six patients suffering from chronic bronchitis were randomized to receive either N-acetylcysteine (NAC) or placebo during a 6-month period. The aim was to compare the number of acute exacerbations in the two groups. General practitioners were asked to enter patients with a di...See full text at original site
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引用元：
https://doi.org/10.1016/0007-0971(87)90182-3

データ提供：米国国立医学図書館（NLM）

N-acetylcysteine (NAC) for Chronic Bronchitis: Exploring Its Potential

This study investigates the potential therapeutic benefits of N-acetylcysteine (NAC) for patients suffering from chronic bronchitis. The authors conducted a randomized, controlled trial to compare the efficacy of oral NAC versus placebo in reducing the number of acute exacerbations in patients with chronic bronchitis. While the study did not find a significant difference in the number of exacerbations, it did reveal a trend towards improvement in the NAC group during the initial 3 months of the trial. This research suggests that NAC may have some potential benefits for patients with chronic bronchitis, warranting further investigation.

NAC for Chronic Bronchitis: Exploring Its Potential Benefits

This research suggests that NAC may have some potential benefits for patients with chronic bronchitis. While the study did not find a significant difference in the number of exacerbations, the trend towards improvement in the NAC group during the initial 3 months suggests that NAC may play a role in managing the symptoms of chronic bronchitis. This research underscores the importance of exploring alternative treatment options for chronic bronchitis, potentially improving patient outcomes and quality of life.

Managing Chronic Bronchitis: A Comprehensive Approach

This research highlights the importance of a comprehensive approach to managing chronic bronchitis. The study's findings suggest that NAC may offer potential benefits, but further research is needed to determine its optimal role in treatment. This underscores the need for ongoing research and exploration of alternative therapies for chronic bronchitis, ensuring patients receive the most effective and personalized care possible.

Dr.Camel's Conclusion

Dr. Camel, a scholar who has witnessed the resilience of desert plants, sees this research as a reminder that even seemingly small changes can have a significant impact. He compares the potential benefits of NAC for chronic bronchitis to the way desert plants adapt to their harsh environment, finding ways to thrive even in challenging conditions. This research underscores the importance of exploring diverse therapeutic options, potentially unlocking new avenues for managing complex chronic conditions.

Date :
  1. Date Completed 1988-06-14
  2. Date Revised 2019-10-22
Further Info :

Pubmed ID

3329530

DOI: Digital Object Identifier

10.1016/0007-0971(87)90182-3

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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