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Clinical implementation of preemptive pharmacogenomics in psychiatry: Τhe "PREPARE" study.

Author: , AssimakopoulosK, FerentinosP, GeorgilaE, GourzisP, PatrinosG P, SkokouM, TsermpiniE E

Clinical Trial ProtocolA plan for conducting a clinical trial. It describes in detail the purpose, design, methodology, and statistical considerations of the trial, ensuring the transparency and consistency of the trial.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

PREPARE, the first prospective pharmacogenomics study in Europe, aims to reduce the occurrence and severity of drug-genotype-associated adverse drug reactions (ADRs) in psychiatric patients. The study will recruit 1500 patients who will receive either standard or pharmacogenomic-guided treatment for depression or psychosis. The study aims to demonstrate that pharmacogenomic-guided treatment can reduce ADRs by 30% compared to standard care.
Paper Details　
Original Abstract of the Article :
PREemptive Pharmacogenomic testing for Preventing Adverse drug REactions (PREPARE) is the first prospective, pre-emptive pharmacogenomic study conducted in Europe, within the frame of the Horizon 2020 program. It aims to determine whether implementing pre-emptive pharmacogenomics (PGx) testing of cl...See full text at original site
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引用元：
https://doi.org/10.22365/jpsych.2020.314.341

データ提供：米国国立医学図書館（NLM）

PREPARE: A Groundbreaking Study Utilizing Pharmacogenomics in Psychiatry

Psychiatry, like a vast and intricate desert, often presents challenges in finding the right medication for each patient. This study explores the potential of pharmacogenomics, a field that examines the impact of genetic variations on drug responses, to personalize psychiatric treatment.

The PREPARE study is a groundbreaking prospective study that aims to determine whether implementing preemptive pharmacogenomics testing in psychiatric patients can reduce the occurrence and severity of drug-related adverse events. The study will compare two groups of patients, one receiving standard treatment and the other receiving pharmacogenomics-guided treatment.

Personalized Psychiatry: A New Horizon for Patient Care

The PREPARE study promises to revolutionize psychiatric treatment by personalizing drug selection and dosage based on individual genetic profiles. The study's findings could lead to more effective and safer treatments for patients, minimizing the risk of adverse events and improving patient outcomes.

Empowering Patients: A Future of Personalized Psychiatry

The PREPARE study, like a shimmering oasis in the vast desert of psychiatric care, promises to empower patients by providing them with personalized treatment plans tailored to their unique genetic profiles. This personalized approach to psychiatric care holds the potential to improve treatment effectiveness, minimize adverse events, and enhance patient quality of life.

Dr.Camel's Conclusion

This study, like a beacon of hope in the vast desert of psychiatric research, shines a light on the potential of pharmacogenomics to revolutionize patient care. The PREPARE study is a groundbreaking initiative that could lead to a new era of personalized psychiatry, where treatments are tailored to each individual's unique genetic makeup, paving the way for more effective and safer therapies.

Date :
  1. Date Completed 2021-10-06
  2. Date Revised 2021-10-06
Further Info :

Pubmed ID

33361064

DOI: Digital Object Identifier

10.22365/jpsych.2020.314.341

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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