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Self-Reported Allergy to Thyroid Replacement Therapy: A Multicenter Retrospective Chart Review.

Author: BernetVictor J, Carrillo-MartinIsmael, Chamorro-ParejaNatalia, Gonzalez-EstradaAlexei, HaehnDaniela A, ParkMiguel A, WestphalSydney A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.

Overview

This study explores patterns of adverse drug reactions, including immediate hypersensitivity and predictable reactions, to thyroid replacement therapy (TRT), specifically levothyroxine (LT4), which is widely prescribed in the United States. While immediate hypersensitivity reactions are rare, the study aims to identify common patterns of adverse reactions.
Paper Details　
Original Abstract of the Article :
To determine patterns of adverse drug reactions (ADRs), including immediate drug hypersensitivity reactions (DHRs) and predictable ADRs, to thyroid replacement therapy (TRT). TRT is the treatment of choice for hypothyroidism. Levothyroxine (LT4) is among the most commonly prescribed medications in t...See full text at original site
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引用元：
https://doi.org/10.4158/EP-2019-0488

データ提供：米国国立医学図書館（NLM）

Thyroid Replacement Therapy: Exploring Adverse Reactions

This study investigates the prevalence and patterns of [adverse drug reactions] to [thyroid replacement therapy] (TRT). The researchers conducted a multicenter retrospective chart review to analyze reported adverse reactions, including immediate drug hypersensitivity reactions and predictable adverse drug events. Their findings provide valuable insights into the safety profile of TRT, a common treatment for hypothyroidism.

Unveiling the Safety Profile of Thyroid Replacement Therapy

The study found that documented immediate drug hypersensitivity reactions to TRT are rare, with only a few case reports. This suggests that TRT is generally well-tolerated. However, the researchers also identified predictable adverse drug events, highlighting the importance of careful monitoring and individualized treatment plans.

Navigating Thyroid Replacement Therapy

This study underscores the importance of understanding the potential adverse reactions associated with TRT. While TRT is generally safe, it's essential to work closely with your healthcare provider to monitor for any potential side effects and ensure a safe and effective treatment course. Just as a desert traveler must be vigilant about hydration, it's important to be mindful of the potential side effects of any medication.

Dr.Camel's Conclusion

This study sheds light on the safety profile of thyroid replacement therapy, highlighting the importance of careful monitoring and individualized treatment plans. While TRT is generally well-tolerated, it's essential to be aware of potential side effects and work closely with healthcare professionals to ensure a safe and effective treatment course.

Date :
  1. Date Completed 2021-01-22
  2. Date Revised 2021-01-22
Further Info :

Pubmed ID

33471645

DOI: Digital Object Identifier

10.4158/EP-2019-0488

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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