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Efficacy of opioid receptor modulators in patients with irritable bowel syndrome: A systematic review and meta-analysis.

Author: ChenTing, LiBo, LiXia, MaJinxin, QinJinyan, ShiXiaoshuang, TangXudong, WangFengyun, WuHaomeng, ZhangJiaqi

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This study aims to determine whether medications that affect opioid receptors in the body can help improve symptoms of irritable bowel syndrome (IBS). IBS is a common digestive disorder that can significantly impact people's lives, and this study seeks to find potential treatments by examining the role of opioid receptors in gut function.
Paper Details　
Original Abstract of the Article :
While irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal diseases in clinical practice, it has diverse pathogenesis. Because of its sudden and lingering intractable symptoms, it seriously affects patients work and life. Opioid receptors are G protein-coupled recepto...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850711/

データ提供：米国国立医学図書館（NLM）

Opioid Receptor Modulators: A Potential Oasis for Irritable Bowel Syndrome

Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by abdominal pain, bloating, and altered bowel habits. This systematic review and meta-analysis assessed the efficacy of opioid receptor modulators in treating IBS. The authors explored the role of opioid receptors in regulating gastrointestinal function and reviewed studies examining the effects of opioid receptor modulators on IBS symptoms. The findings suggest that these modulators may hold potential for improving IBS symptoms, though further research is needed to confirm their efficacy and safety.

Opioid Receptor Modulators: A New Frontier in IBS Treatment

The findings of this meta-analysis offer a glimmer of hope for individuals struggling with IBS. While more research is needed to confirm their effectiveness, opioid receptor modulators represent a potential new avenue for treating IBS symptoms. This could provide a valuable alternative for patients who haven't found relief from traditional therapies. The study's findings encourage further investigation into the role of opioid receptor modulation in managing IBS.

Managing IBS: A Journey Through the Desert of Discomfort

Living with IBS can be a challenging experience, impacting daily life and well-being. This review underscores the importance of exploring various treatment options, including medication, dietary adjustments, and lifestyle modifications. By working closely with their healthcare providers, individuals with IBS can find a personalized approach to managing their symptoms and improving their quality of life.

Dr. Camel's Conclusion

The search for effective IBS treatments is like traversing a vast desert, searching for a source of relief. This review offers a promising glimpse into the potential of opioid receptor modulators as a new oasis in the landscape of IBS management. While further research is needed, it provides a beacon of hope for those seeking a more comfortable and fulfilling life with IBS.
Date :
  1. Date Completed 2021-02-10
  2. Date Revised 2023-09-19
Further Info :

Pubmed ID

33530231

DOI: Digital Object Identifier

PMC7850711

SNS
PICO Info
in preparation
Languages

English

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