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Clinical comparison of systemic methylprednisolone acetate versus topical budesonide in patients with seasonal allergic rhinitis.

Author: BlaserM, GrafW, KlintT, PichlerW J, SauterK, WeissS, WitschiK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Budesonide nasal spray and methylprednisolone acetate injection were compared for treating seasonal allergic rhinitis. Both treatments significantly improved symptoms, but budesonide was more effective in reducing nasal symptoms, while methylprednisolone was more effective in reducing the need for eyedrops. Both treatments were well-tolerated.
Paper Details　
Original Abstract of the Article :
Thirty patients with seasonal allergic rhinitis entered a double blind study comparing budesonide (nasal spray, 400 micrograms/d) and i.m. injection of 80 mg methylprednisolone acetate. Symptoms were assessed over a "run in" period of 3-7 days followed by a treatment period of 3 weeks. Pollen counts...See full text at original site
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引用元：
https://doi.org/10.1111/j.1398-9995.1988.tb00399.x

データ提供：米国国立医学図書館（NLM）

Seasonal Allergies: Budesonide vs. Methylprednisolone Acetate

Seasonal allergies can be a real nuisance, often causing sniffles, sneezes, and itchy eyes. This study compares the effectiveness of two different treatments for seasonal allergic rhinitis: budesonide nasal spray and a single injection of methylprednisolone acetate. The research aims to determine which treatment provides better relief from allergy symptoms and whether there are any significant side effects.

A Nose for Relief: Budesonide Takes the Lead

The study found that both treatments effectively reduced allergy symptoms, but budesonide emerged as the winner when it came to nasal symptoms like itching, sneezing, and runny nose. Both treatments had minimal side effects, making them safe and tolerable options.

Navigating the Hayfever Maze

This research offers helpful insights for those struggling with seasonal allergies. It suggests that budesonide nasal spray can be a good choice for managing nasal symptoms. However, it's important to remember that each individual's response to treatment may vary. Just as a camel finds its way through the desert, it's important to work with a doctor to find the best approach for managing allergy symptoms.

Dr. Camel's Conclusion

Finding the right treatment for seasonal allergies can be like searching for a cool oasis in the middle of a hot desert. This research suggests that budesonide nasal spray can be a effective option for managing those bothersome nasal symptoms. Remember, the journey to allergy relief is unique for each person, so working with a doctor to find the right treatment is key.

Date :
  1. Date Completed 1988-06-02
  2. Date Revised 2019-08-20
Further Info :

Pubmed ID

3364627

DOI: Digital Object Identifier

10.1111/j.1398-9995.1988.tb00399.x

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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