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Everolimus therapy and side‑effects: A systematic review and meta‑analysis.

Author: ArenaClaudia, BizzocaMaria Eleonora, CaponioVito Carlo Alberto, LeuciStefania, Lo MuzioLorenzo, TroianoGiuseppe, ZhurakivskaKhrystyna

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review aimed to evaluate the type and incidence of side effects in patients treated with everolimus. The primary adverse events reported were stomatitis, leukopenia, anorexia, anemia, and fatigue, with the majority of patients experiencing grade 1 or 2 adverse events.
Paper Details　
Original Abstract of the Article :
Recent studies have focused on identifying novel targeted agents in order to reduce the undesired side‑effects of conventional chemotherapeutic agents on normal cells. However, even targeted therapies may exert certain negative effects on healthy tissues. The present systematic review was performed ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/34132370

データ提供：米国国立医学図書館（NLM）

Everolimus: Navigating the Side Effects of a Targeted Therapy

In the vast landscape of cancer treatment, targeted therapies are like oases in the desert, promising more precise attacks on cancer cells while minimizing harm to healthy tissues. This study investigates the side effects of everolimus, a targeted therapy, looking for hidden dangers in this oasis.

Side Effects: Hidden Dangers in the Oasis

The most common side effects reported were stomatitis, leukopenia, anorexia, anemia, and fatigue. This is like a mirage in the desert, where the promise of relief is often accompanied by unforeseen challenges. Most side effects were mild, suggesting everolimus's relative safety compared to conventional chemotherapy.

Navigating the Oasis with Caution

While everolimus offers a beacon of hope for cancer patients, it's important to be aware of its potential side effects. It's like navigating the oasis with caution, knowing that the beauty of the oasis can sometimes be deceptive.

Dr.Camel's Conclusion

This review highlights the importance of understanding the potential side effects of targeted therapies, even those that appear safer than conventional treatments. It's a reminder that even in the oasis of targeted therapies, there are still challenges to overcome.

Date :
  1. Date Completed 2021-12-06
  2. Date Revised 2021-12-14
Further Info :

Pubmed ID

34132370

DOI: Digital Object Identifier

54

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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