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Detection of unknown ototoxic adverse drug reactions: an electronic healthcare record-based longitudinal nationwide cohort analysis.
Author: ChaJaehun, KimDong-Kyu, KimJong-Yeup, LeeSuehyun, SonGil Myeong
Original Abstract of the Article :
Ototoxic medications can lead to significant morbidity. Thus, pre-marketing clinical trials have assessed new drugs that have ototoxic potential. Nevertheless, several ototoxic side effects of drugs may remain undetected. Hence, we sought to retrospectively investigate the potential risk of ototoxic...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8263785/
データ提供:米国国立医学図書館(NLM)
Unraveling the Hidden Dangers of Ototoxic Drugs: A Nationwide Cohort Study
This study takes us on a journey into the world of ototoxic drugs, medications that can harm our ears. It's like venturing into a vast desert with a treasure map - we're seeking the hidden dangers of these drugs, hoping to protect our hearing. The researchers used a clever approach, analyzing electronic health records from a large cohort in South Korea to identify potential ototoxic reactions to common drugs. This study provides a fascinating glimpse into the vast landscape of drug safety and the potential for unexpected side effects.
Unveiling Hidden Ototoxicity in Common Medications
The study's findings are truly enlightening, like discovering a hidden oasis in a desert. It reveals that certain medications, such as hydroxyzine and sucralfate, may increase the risk of hearing loss. This discovery shines a light on the importance of closely monitoring patients who are taking these medications, particularly those already at risk for ototoxicity. The researchers found that the adjusted hazard ratio of bilateral hearing loss was 2.20 (1.05-4.60) in hydroxyzine users and 2.26 (1.18-4.33) in sucralfate users.
Protecting Our Hearing: A Reminder from the Desert
This study serves as a timely reminder that even seemingly innocuous medications can have unexpected consequences. It's important to keep in mind that the desert of medicine is filled with surprises. While we may be able to prevent some of these dangers by avoiding co-administration of ototoxic medications, it's essential to be vigilant and aware of potential side effects. It's also critical to inform our healthcare providers about all medications we are taking and any history of hearing loss. This proactive approach can help us navigate the complexities of medicine and safeguard our health.
Dr.Camel's Conclusion
It's always fascinating to see how medicine, like the vast desert, continues to reveal its secrets. This study showcases the power of data analysis in uncovering potential health risks. We must remain curious and vigilant, constantly seeking to understand the complexities of our bodies and the medications we take. It's a reminder that even in the seemingly familiar, there are always new things to learn and new ways to protect our health.
Date :
- Date Completed 2021-11-24
- Date Revised 2021-11-24
Further Info :
Related Literature
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