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Topical chlormethine gel in the treatment of mycosis fungoides: A single-center real-life experience and systematic review of the literature.

Author: ArdigòMarco, FranceschiniChiara, La MalfaAntonia Marina, LaghiAlessandro, MandelVictor Desmond, MusiccoFelice, SansoneMassimo, TeoliMiriam

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Chlormethine gel (CG) has become a prominent treatment for mycosis fungoides (MF). This study evaluated the frequency of CG use for MF treatment and determined its limits and potentialities in a real-world setting. A systematic review of articles, combined with a single-center real-life experience, showed high clinical response rates with good safety and tolerance, supporting CG's versatile use in MF treatment.
Paper Details　
Original Abstract of the Article :
Gel formulation of chlormethine (CG) has gained a preeminent role among therapies available for mycosis fungoides (MF). To evaluate the frequency of use of CG for MF treatment and to determine the limits and potentialities of CG in a real-world setting. A systematic review of articles published prio...See full text at original site
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引用元：
https://doi.org/10.1111/dth.15683

データ提供：米国国立医学図書館（NLM）

Topical Chlormethine Gel: A Versatile Treatment for Mycosis Fungoides

The treatment of [mycosis fungoides (MF)], a type of [cutaneous T-cell lymphoma], continues to evolve. This research investigates the [efficacy and safety] of [topical chlormethine gel (CG)] in the treatment of [MF]. The study combines a [single-center real-life experience] with a [systematic review of the literature] to assess the [clinical effectiveness] of [CG] in a [real-world setting].

Topical Chlormethine Gel: A Promising Treatment for Mycosis Fungoides

The study highlights the [prominent role] of [CG] in the [management of MF]. The researchers found a [high response rate] to [CG] treatment in their [single-center experience], exceeding the [response rates reported in other real-world studies]. This finding reinforces the [potential of CG] as a [valuable treatment option] for [MF].

Mycosis Fungoides Treatment: A Multifaceted Approach

This research emphasizes the [versatility] of [CG] as a [treatment modality] for [MF]. The study highlights the [adaptability of dose and application rate], allowing for [personalized treatment plans] tailored to the [individual needs] of each patient. The researchers note that [CG] has a [favorable safety profile], making it a [well-tolerated treatment option] for [patients with MF].

Dr. Camel's Conclusion

This study is like a [desert camel] carrying a [precious cargo] of [hope and effective treatment] for those battling [mycosis fungoides]. The research highlights the [efficacy and versatility] of [topical chlormethine gel], offering a [new path] for [managing this challenging condition]. This research reminds us that [ongoing research] is crucial for [developing effective treatments] and [improving outcomes] for those facing [complex skin diseases].

Date :
  1. Date Completed 2022-09-08
  2. Date Revised 2022-12-05
Further Info :

Pubmed ID

35778940

DOI: Digital Object Identifier

10.1111/dth.15683

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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