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Prevention of rheumatoid arthritis: A systematic literature review of preventive strategies in at-risk individuals.

Author: FrazzeiGiulia, MustersAnne, TasSander W, de VriesNiek, van VollenhovenRonald F

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Rheumatoid arthritis (RA) is a chronic autoimmune disease that can cause severe joint damage and disability. Before RA develops, there's a preclinical stage where people with a genetic predisposition accumulate factors that increase their risk. Treating people at risk before they develop RA could potentially prevent or delay the disease and have a positive impact on their lives and society.
Paper Details　
Original Abstract of the Article :
Rheumatoid arthritis (RA) is an autoimmune disease characterized by symmetrical peripheral polyarthritis in the hands and/or feet, leading to long-term disability if not treated effectively. RA is preceded by a preclinical phase, in which genetically predisposed individuals accumulate environmental ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/j.autrev.2022.103217

データ提供：米国国立医学図書館（NLM）

Rheumatoid Arthritis: A Journey Through the Sands of Time

This study takes us on a journey through the complex world of rheumatoid arthritis (RA), a chronic inflammatory disease that can affect the joints, causing pain, stiffness, and swelling. The researchers delve into the preclinical phase, a period before the disease fully manifests. This is like studying the subtle changes in a desert landscape, indicating the potential for an upcoming sandstorm. The study explores the potential for early intervention, like creating a protective barrier against the sandstorm, to delay or even prevent the onset of RA.

The Promise of Early Intervention

This research highlights the importance of early intervention in autoimmune diseases, a concept like planting seeds of hope in the desert. It's about catching the disease early, before it takes root and causes significant damage. By identifying individuals at risk and providing timely treatment, we can potentially alter the course of the disease and improve their lives.

A Journey of Prevention and Wellness

This study emphasizes the importance of preventative strategies in maintaining good health. It's like preparing for a long desert journey, ensuring you have the necessary resources and knowledge to navigate the challenges ahead. By understanding the risk factors for RA and taking steps to mitigate them, we can potentially reduce the burden of this debilitating disease.

Dr. Camel's Conclusion

This research highlights the potential of early intervention in rheumatoid arthritis, emphasizing the need for personalized strategies to prevent or delay disease onset. It's like planting seeds of hope in the desert, with the potential to blossom into a healthier future for those at risk.

Date :
  1. Date Completed 2022-12-27
  2. Date Revised 2023-02-23
Further Info :

Pubmed ID

36280095

DOI: Digital Object Identifier

10.1016/j.autrev.2022.103217

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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