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Novel and emerging treatment options for acne vulgaris
Author: AuffretNicole, BallangerFabienne, ClaudelJean Paul, DrenoBrigitte, LecciaMarie-Thérèse
Original Abstract of the Article :
The principal actors in acne are the sebaceous gland, keratinocytes of the follicle and skin microbiome/innate immunity. Current acne treatments are frequently accompanied by side effects or may cause antibacterial resistance. New formulations and emerging treatments with novel mechanisms of action ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1684/ejd.2022.4306
データ提供:米国国立医学図書館(NLM)
New and Emerging Treatments for Acne Vulgaris: A Comprehensive Overview
Acne vulgaris, a common skin condition, has plagued humanity for centuries. The quest for effective treatment strategies has been a long and winding road, much like a camel's journey across a vast desert. This comprehensive review provides an update on the latest advancements in acne therapy, exploring both novel and existing treatments. The review focuses on recent research and clinical trials, highlighting the multifaceted nature of acne and the various therapeutic approaches being developed. The authors emphasize the critical role of the sebaceous gland, keratinocytes of the follicle, and skin microbiome in the development of acne. They highlight the limitations of current treatments, including the potential for side effects and the emergence of bacterial resistance. The review then delves into the exciting world of novel treatments, outlining the mechanisms of action and potential benefits of new formulations and emerging therapies. The authors discuss promising compounds like Clascosterone, Trifarotene, and Sarecy-cline, as well as more effective and well-tolerated formulations of existing treatments, such as Minocycline, Tretinoin, Tazarotene, and Lidose-isotretinoin. They also explore emerging therapies targeting the sebaceous gland, inflammation, and skin microbiome, including hyaluronic acid, cannabidiol, modulators of the skin microbiota, insulin-like growth factor, vaccines, bacteriophages, probiotics, and antimicrobial peptides. The review concludes by emphasizing the potential of these new and emerging treatments to significantly reduce the prevalence of acne worldwide.
Fighting Acne with Innovative Approaches
This review paints a promising picture for individuals battling acne. The increasing availability of novel treatments, coupled with improved formulations of existing therapies, offers renewed hope for effective and well-tolerated solutions. The authors highlight the potential of emerging therapies targeting specific aspects of acne pathogenesis, suggesting a future where personalized treatments are tailored to the individual needs of each patient.
A New Era of Personalized Acne Treatment
The insights presented in this review underscore the need for a more personalized approach to acne treatment. Just as camels navigate different terrains and adapt to diverse environments, individuals with acne require tailored treatment strategies to effectively address their unique skin conditions. The ongoing development of novel and targeted therapies offers exciting possibilities for the future of acne management, empowering individuals to achieve clearer skin and enhanced self-confidence.
Dr. Camel's Conclusion
This comprehensive review offers a refreshing glimpse into the evolving landscape of acne treatment. The quest for effective and safe solutions continues, with promising new therapies on the horizon. As we traverse the desert of acne research, this review serves as a valuable roadmap, guiding us towards a future where effective treatments are available for everyone. The relentless pursuit of innovative therapies holds the key to unlocking a future where acne is no longer a source of distress but a manageable condition.
Date :
- Date Completed 2022-10-31
- Date Revised 2022-10-31
Further Info :
Related Literature
English
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